CNS Pharmacology-Wk10

Question 1

Some of the more frequent side effects seen in patients taking antiepileptic drugs that may affect physical therapy are:

Answer 1

headache, dizziness, sedation, GI issues

Question 2

In a patient with Parkinson’s disease, using physical therapy interventions to maintain motor function can ___________ the need for anti-Parkinson’s drugs.

Answer 2

decrease

Question 3

Parkinson disease typically occurs because of the slow, progressive degeneration of specific ______________-secreting neurons in the ______________.

Answer 3

dopamine, substantia nigra of the basal ganglia

Question 4

The use of levodopa and several other medications has allowed many patients with Parkinson disease to remain active despite the disease’s steadily degenerative nature. (T/F)

Answer 4

True

Question 5

Despite levodopa being the most effective pharmacological treatment for parkinsonism, one of the most serious problems associated with levodopa therapy is:

Answer 5

The drug becomes less effective when it is administered for prolonged periods

Question 6

Benzodiazepines and other drugs used to treat sleep disorders and anxiety are often associated with falls and subsequent trauma, including hip fractures, especially in older adults (T/F)

Answer 6

True

Question 7

Therapists can help plan and implement non-pharmacological interventions to help decrease anxiety and improve sleep by

Answer 7

interventions such as yoga, regular exercise, and massage
decreasing the need for drugs and thus decreasing drug related side effects
reviewing patient’s sleeping habits and suggesting improvements in sleep hygiene

Question 8

Newer or “atypical” antipsychotics are often preferred because:

Answer 8

they have a reduced risk of causing motor side effects

Question 9

Antidepressant drugs that selectively affect 5-hydroxytryptamine neurotransmission may also cause “serotonin syndrome” which is characterized by:

Answer 9

shivering, sweating, movement disorders

Question 10

The classic symptoms of Parkinson’s disease include

Answer 10

rigidity, resting tremor, bradykinesia, postural instability

Question 11

The rationale for use of levodopa in treating Parkinson’s disease include

Answer 11

attempts to increase dopamine content in basal ganglia as direct administration of dopamine cannot cross the BBB

Question 12

The optimal treatment time for rehabilitation for patient’s who are taking Parkinson drugs is

Answer 12

30-60 minutes

Question 13

One of the most concerning adverse effects of sedative-hypnotic/antianxiety drugs is the significant increased risk of

Answer 13

falls

Question 14

Rehabilitation concerns with antidepressant medications include

Answer 14

time lag, change of increased depression during initial treatment, recognition of mood changes

Question 15

The goals of drug therapy in dementia include

Answer 15

improve cognitive and intellectual function, improve/ modify behavior

Question 16

The primary concern for all antipsychotic medications is extrapyramidal (motor) side effects including tardive dyskinesia, pseudoparkinsonism, akathsia, and other dystonias (T/F)

Answer 16

true