Endocrine Patho

Question 1

pathophysiology of type 1 diabetes mellitus

Answer 1

beta cells in pancreas are destroyed, there are idiopathic types and immune-medicated types. 1. permanent insulin deficiency.
2. can induce an autoimmune attack of the beta cells.

Question 2

pathophysiology of type 2

Answer 2

resistant to insulin action in target tissues and have abnormal insulin secretion.

Question 3

acute and chronic complications of both

Answer 3

acute

• ketoacidosis
• hypoglycaemia
• hyperglycaemia

chronic

• nerve damage
• kidney damage
• heart and blood vessel disease