Cardiovascular Patho Flashcards
Risk factors of atherosclerosis
- non-modifiable are age, gender and genetics
- modifiable are obesity, smoking, sedentary lifestyle, diabetes and hypertension
pathogenesis of atherosclerosis
caused by endothelial damage to the arteries and inflammatory cells and platelets disrupt the endothelium. LDLs and macrophages get stuck to the wall causing atherosclerotic lesions and fibrous plaque to form which can cause a rupture or blockage in the artery.
complications of atherosclerosis
- arrhythmia
- heart attack
- angina pectoris
- heart failure
development of hypertension
- primary is unknown
- secondary results from renal and endocrine disease
- malignant is uncontrollable
adverse effects/complications of hypertension
long periods of time the pressure can cause damage to arterial walls they can become hard and thick and narrows the lumen, potential to cause an aneurysm, ischaemia and necrosis to parts of the body.
three types of angina
- stable angina
- variant angina
- unstable angina
Pathophysiology of myocardial infarction
occurs when there is a complete obstruction tot he coronary artery, leading to prolonged ischaemia
cause of dysrhythmias
can be caused by MI, angina, electrolytes imbalances, hypoxia and thyroid diseases
clinical manifestations of dysrhythmias
angina, dizziness, palpitations, shortness of breath, pounding in the chest
risk factors for heart failure
hypertension, ishaemic heart disease and venous insufficiency
three primary cardiac parameters in heat failure
preload, after-load and inotropy
how does cardiac compensations manifest in the disease state
the heart beats faster ( which increases your heart rate).
Pump more blood with each beat (increase your stroke volume).