Endocrine Health Flashcards

1
Q

Describe the stages of the Hypothalamus-Pituitary-Tyroid axis?

A

Thyrotropin-release hormone (TRH) - Hypothalamus
stimulates
Thyroid-stimulating hormone (TSH)
stimulates
Thyroid hormone release T4 (around 90%) and T3

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2
Q

What enzymes are key for the tyroid?

A

Selenoproteins

Deiodinase - 1 & 2 convert T4 to T3

Deiodinase 3 - converse T4 to Reverse T3

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3
Q

What is T3

A

Triiodothyronine
4x the ‘strength’ of T4
Increases grow, bone and CNS development
Increases BMR, heart rate and activates the metabolism.

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4
Q

What is T4?

A

Thyroxine
Weak thyroid activity ‘inactive form

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5
Q

What is Reverse T3

A

Biologically inactive - one hypothesis is it protects tissues from excess thyroid hormones

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6
Q
A
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