Endocrine glands (Lesson 5) Flashcards
What are the endocrine glands (organs)?
Hypophysis
Epiphysis
Thyroid gland
Parathyroid glands
Adrenal grlands
Pancreas (Islets of Langerhans)
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Hypophysis - Neurohypophysis
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Hypophysis - Adenohypophysis, pars distalis, HE staining
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What are the endocrine cells of the adenohypophysis?
Basophils:
- Thyreotropic cells - TSH
- Gonadotropic cells - FSH, LH
- Corticotropic cells - ACTH
Acidophils:
- Somatotropic cells - STH
- Mammotropic cells - prolactin
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Hypophysis - Adenohypophysis, pars distalis, HE staining
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Thyroid gland (glandula thyroidea):
- Follicles
- Squamous to columnar epithelium
- Depends of the secretory activity
- Content = colloid - thyroglobulin
- Follicular cells
- Parafollicular cells
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Parafollicular cells (c) in the thyroid gland
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Parafollicular cells (c) in the thyroid gland
Describe the parathyroid gland
- Connective tissue captule
- Trabecules of epithelial cells - sometimes compact masses of cells
- Visceral type of capillaries (fenestrated)
- Chief cells:
- Small polygonal cells
- Vesicular
- Pale staining nucleus
- Secretory granules - parathormone
- Variable amount of glycogen
- Oxyphil cells - darker nuclei, number of mitochondria
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Parathyroid gland
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Parathyroid gland
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Parathyroid gland
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Describe the adrenal gland
- Cortex:
- Mesodermal origin - coelomic epithelium
- Steroid secreting cells
- Medulla:
- Originates from the neural crest
- Cells produce catecholamines
Cortex:
- Zona glomerulosa (aldosterone)
- Zona fasciculata (glucocorticoids - cortisol, androgens)
- Zona reticularis (androgens, glucocorticoids)