Endocrine Glands Flashcards

1
Q

Membrane impermeable hormones

A
  • Peptides and proteins
  • Glycoproteins
  • Modified AAs
  • Receptors are on the membrane
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2
Q

Membrane permeable hormones

A
  • Steroid and thyroid hormones

- Receptors are intracellular

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3
Q

Characteristics of cells producing protein hormones

A
  • Abundant RER
  • Prominent Golgi
  • Hormones in secretory granules
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4
Q

Characteristics of cells producing steroid hormones

A
  • Centrally located nucleus
  • Lipid droplets
  • Abundant smooth ER
  • Spherical mitochondria with tubular or vesicular cristae
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5
Q

Three regions of adenohypophysis

A
  • Pars tuberalis
  • Pars distalis
  • Pars intermedia
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6
Q

Chromophils

A
  • Cells in the anterior pituitary that contain secretory granules that stained.
  • Basophils and acidophils
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7
Q

Chromophobes

A
  • Cells in anterior pituitary that don’t stain well

- Stem/progenitor cells

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8
Q

Acidophils

A

-Produce growth hormone (somatotropin) and prolactin

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9
Q

Basophils

A

-Produce FSH, LH, TSH and ACTH, B-LPH

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10
Q

Pars intermidea

A
  • Largely inactive

- Colloid filled follicles and cysts

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11
Q

Neurohypophysis

A
  • Posterior pituitary
  • No secretory granules
  • Contains axons of neurons and glial cells
  • Secretes ADH and oxytocin stored in Herring bodies
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12
Q

Adrenal cortex

A
  • Typical steroid producing cells
  • Epithelial origin
  • 3 zones
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13
Q

Adrenal medulla

A
  • Neuronal origin
  • Electron dense secretory granules that react with chromium and silver salts
  • Catecholamines
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14
Q

Zona glomerulosa

A

-Mineral corticoids (aldosterone)

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15
Q

Zone fasciculata

A

-Glucocorticoids (cortisol)

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16
Q

Zona reticularis

A

-Sex hormones (cortisol and weak androgen DHEA)

17
Q

Follicular cells

A
  • Protein secreting cells in thyroid

- Cuboidal to low columnar

18
Q

Parafollicular cells

A
  • Also called C cells
  • Larger than follicular cells
  • Pale in preparation
  • Basal lamina of follicles or between follicles
  • Produce calcitonin–promotes calcification of bone
19
Q

Chief cells

A
  • In parathyroid glands
  • Pale staining, acidophilic
  • Produce PTH
20
Q

Oxyphil cells

A
  • Large cells in parathyroid glands
  • Highly acidophilic
  • Unknown function