Endocrine Disorders - Causes

Question 1

Diabetes Insipidus

Answer 1

• Primary (acute) vasopressin deficiency: Pituitary or hypothalamus defect: tumor, head trauma, infection, metastatic tumors, radiation,pressure of brain hemorrhage.
• Nephrogenic: inherited disorder-renal tubules don’t respond to ADH
• Drug-related: Lithium, glucocorticoids, democlocycline

Question 2

SIADH

Answer 2

• Malignancies- esp. of the lungs
• Pulmonary: pneumonia/pneumothorax
• CNS: trauma, infection, strokes
• Drugs: opioids, SSRIs, anesthesia Hypothyroidism and other things.

Question 3

Cushing Syndrome

Answer 3

• endogenous cortisol secretion by pituitary or adrenal adenomas
• malignancies of the lung, GI or pancreas.

Question 4

Hyperaldosteronism

Answer 4

• adrenal adenoma