Endocrine communication Flashcards
endocrine system
a communication system using hormones as signalling molecules.
hormones
molecules that are released by endocrine glands directly into the blood. They act as messengers, carrying a signal from the endocrine gland to a specific target organ or tissue.
target cells (for non steroid hormones)
cells that possess a specific receptor on their plasma membrane. The shape of the receptor is complementary to the shape of the hormone molecule. Many similar cells together form a target tissue.
What circulatory system does the endocrine system use to transport its signals?
blood.
What are the two types of hormones?
- protein and peptide hormones, imitating amino acids.
(e.g adrenaline, insulin and glucagon) - steroid hormones
(e.g. oestrogen and testosterone)
How do protein hormones work?
they are not soluble in the phospholipid membrane and do not enter the cell. Protein hormones need to bind to the cell surface membrane and release a second messenger inside the cell.
How do steroid hormones work?
can pass through the membrane and enter the cell and the nucleus, to have direct effect on the DNA in the nucleus.
How are hormones released directly into the blood?
The endocrine glands.
What are the endocrine glands
ductless glands
consist of groups of cells that manufacture and release the hormone directly into the blood in capillaries running through the gland.
The endocrine organs in the human body?
- pituitary gland
- thyroid gland
- thymus
- adrenal glands
- pancreas
- ovaries (females)
- testes (males)
What are the cells receiving the endocrine signal called?
target cells
peptide hormones
known as first messengers
signalling molecules outside the cell that bind to the cell surface membrane and initiate an effect inside the cell.
cause the release of another signalling molecule in the cell. known as second messenger stimulates a change in activity of the cell.
first messengers
peptide hormones
second messengers
signalling molecules
G protein
how many peptide hormones act
is activated when hormone binds to the receptor.
It activates an effector molecule.
most molecules enzyme= adenyl cyclase