Endocrine Chapter 10 Flashcards
Scientific name of Pineal Gland
Epiphysis
Pineal Gland regulates the _______ through the production and secretion of ______
Circadian rhythm; melatonin
Important precursors of pineal gland (epiphysis0
Tryptophan + serotonin
Thyroid Gland is located ….
Anterior aspect of the trachea just inferior to the larynx (adams apple)
What are the thyroid hormones
T3 + T4
Thyroid hormone enters the target cell, bind to receptors within the cell’s ______, and initiate _______ of ______ for protein synthesis
Nucleus; transcription of mRNA
Difference between T3 + T4?
T4 has an extra iodine Adam, T3 only has 3
Thyroid hormone affects virtually ____ cell in the body
Every
What does the Thyroid hormones do?
Increase basal metabolic rate, body heat production, regulate tissue growth + development
Someone that has an excess of thyroid hormone:
Typically have a very high activity level, very fidgety, often feel warm, because their metabolism is running fast and often
Someone that has an insufficient amount of thyroid hormone:
Sluggish, tired, cold, their metabolism is moving slow
T/F
The thyroid is the only endocrine gland that stores its hormones extracellularly in large quantities.
TRUE. It stores enough hormones to last 2-3 months!
Calcitonin is released from the ____cells
Parafollicular cells (C-cells)
Calcitonins job is to:
Lower blood calcium levels
Osteoblasts are:
Bone- BUILDING cells. Blast-Building
Osteoclast:
Bone-CRUSHING cells. Breaking down the bone
Calcitonin inhibits _____ activity, inhibiting bone resorption and the release of calcium from the bony matrix.
Osteoclast
Why are parafollicular (C-cells) released?
In response to a rise in blood calcium levels
How does calcitonin counteract the regulatory effects of the parathyroid glands?
By promoting osteoblast activity
Parathyroid glands location:
Very small glands located on the posterior aspect of the thyroid
Parathyroid glands produce and secrete:
Parathyroid hormone (PTH)
Why is PTH an important hormone?
Plays a critical role in controlling calcium concentration in the blood.
PTH increases ____ levels in the blood by _____
Calcium; stimulating 3 target organs. (Skeleton, kidneys, intestine)
Parathyroid hormone (PTH) increases calcium levels by stimulating the skeleton how?
Stimulates osteoclasts (bone crushing) to digest some of the calcium rich bony matrix + release calcium and phosphates into the blood.