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Boards-Endocrine > Endocrine Cancers > Flashcards

Endocrine Cancers Flashcards

1
Q

Papillary carcinoma

A

Good prognosis
Empty appearing nuclei with orphan annie eyes, psammoma bodies, nuclear grooves
Lymphatic invasion common
Inc risk with RET and BRAF mutation, childhood irradiation

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2
Q

Follicular carcinoma

A

Good prognosis
Invades the capsule (unlike follicular adenoma)
Uniform follicles

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3
Q

Medullary carcinoma

A

Cancer if the parafollicular C cells - produces calcitonin
Sheets of cells in amyloid stroma
Hematogenous spread
Commmon in MEN2A and MEN2B (RET mutations)

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4
Q

Undifferentiated/anaplastic carcinoma

A

Older pts
Invades local structures, very poor prognosis
Giant cells and biphasic spindles

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5
Q

Lymphoma

A

associated with Hashimotos

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6
Q

Resection risks

A
  • Hoarseness: due to nicking the recurrent laryngeal nerve
  • Hypoccalcemia: due to removal of the PT glands
  • Resection of the recurrent laryngeal nerve when removing the inferior thyroid artery
  • resenction of the superior laryngeal nerve when removing the superior thyroid artery
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Boards-Endocrine (7 decks)

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