Endocrine, Blood, Lymph Flashcards
Hormones with the words releasing (R) or inhibiting (I) are synthesized and originate from the ________.
Hypothalamus
The receptor for a hydrophobic steroid hormone is________________________.
Intracellular
Where are receptors for hydrophilic amine hormones?
On the plasma membrane and functions through a secondary messenger
The hormone adrenocorticotropic hormone (ACTH) is secreted by the anterior pituitary and targets the adrenal gland cortex. Which of the following corticosteroids (hormones made in the adrenal cortex) targets the kidney for the reabsorption of sodium (Na+) and secretion of potassium?
Antidiuretic hormone (ADH)
The hormone atrial natriuretic peptide (ANP) is secreted by the heart and targets smooth muscles in the arteries, and the distal convoluted tubule of the kidney. This specific hormone causes _____________.
K+ to be reabsorbed in the kidney, and Na+ to be secreted into the urine
Antidiuretic hormone (ADH) is synthesized in the hypothalamus and targets the smooth muscle in the arteries to cause _________.
Systemic vasoconstriction and increase systemic blood pressure
Oxytocin (OT) synthesized in the hypothalamus and stored in the posterior pituitary targets ________.
the uterus in females to cause smooth muscle contraction during childbirth
In order to increase target cell activation by a hormone, the cell can upregulate (increase the number) of _____________.
Receptors
_____________ is a failure of the adrenal cortex to synthesize aldosterone and cortisol.
Addison’s Disease
Renin secreted by the kidney in response to low blood pressure triggers _______________.
RAS (renin-Angiotensin System/Mechanism) to make Angiotensin II that increases systemic blood pressure, and stimulates secretion of aldosterone to reabsorb more Na+
The three steps of hemostasis are _________.
- vascular spasm.
- platelet plug formation
- coagulation
If a blood sample agglutinates when tested with anti-B antibodies, then ________
The B antigen is present and the blood type is B
If an individual with blood type B receives blood from a donor with blood type O, then _______.
There will be no transfusion reaction because O is the universal donor
The maximum number of O2 molecules that can be carried on one hemoglobin molecule is
4
The formation of Prothrombin Activator is a critical step during the series of reactions that occur during _____________.
Coagulation
_________ are leukocytes that specifically target bacteria.
Neutrophils
T-calls and B- calls are specific to ____________.
adaptive/specific immunity
Antibodies are produced by plasma cells that are derived from _______________.
B-cells
Which of the following is not a component of innate immunity?
a. Mucous membranes
b. fever
c. antibodies
d. skin surface
c. antibodies
Cytokines are ______________________.
a. chemicals produced by immune cells that cause apoptosis
b. chemicals produced by viruses that cause autoimmune disorders
c. chemicals produced by immune cells that allow communication
d. chemicals produced by bacteria that cause inflammation
C. chemicals produced by immune cells that allow communication
What are the five classes of antibodies?
IgM, IgA, IgD, IgG, IgE
What are the 3 eradication mechanisms conducted by antibodies?
neutralization, agglutination, and precipitation
Which of the following is classified under active immunity that is naturally acquired?
a. immunity has no memory
b. immunity that is passed from the mother to the fetus
c. immunity that occurs from a vaccination
d. immunity that occurs from a bacterial or viral infection
Immunity that occurs from a bacterial or viral infection
When immunity is passed from the mother to the fetus, it is then __________________.
Passive immunity
What chemical is released during an allergic reaction that can lead to vasodilation causing significant angioedema?
Histamine
- Where is Growth Hormone (GH) produced?
2.What does it target?
- Anterior Pituitary
- Liver, skeletal muscles, long bones
- Where is prolactin (PRL) produced?
- What does it stimulate?
- Anterior Pituitary
- Milk production
- Where is Follicle Stimulating Hormone (FSH) produced?
- What does it target?
- Anterior Pituitary
- Follicle development in ovaries OR sperm development by the testes.
- Where is Luteinizing hormone (LH) produced?
- What does it trigger?
- Anterior Pituitary
- Ovulation/Testosterone
- Where is Thyroid Stimulating hormone (TSH) produced?
- What does it influence?
- Anterior Pituitary
- Growth and activity of thyroid gland
- Where is Adrenocorticotropic hormone (ACTH) produced?
- What does it regulate?
- Anterior pituitary
- endocrine activity on Adrenal cortex
- Where is Oxytocin (OT) stored?
- What does it target?
- Posterior Pituitary
- Uterus, epididymis, mammary glands
- Where is Antidiuretic hormone (ADH) stored?
- What does it target & cause?
- Posterior Pituitary
- Kidney & increase in BP
- What two hormones does the pancreas produce?
- Which type of cells produces each?
- Insulin produced by beta cells
- Glucagon produced by alpha cells
- Where is Aldosterone produced?
- What does it increase?
- Adrenal Cortex
- Blood volume
- Where is Cortisol produced?
- What are its effects?
- Adrenal Cortex
- Helps resist stress & increases blood glucose
Where are androgens and estrogens produced?
Adrenal Cortex
Adrenal Medulla produces what specific catecholamines?
Dopamine, Epinephrine, and NorEpinephrine
What hormone is produced by the kidneys?
Renin
1.What does the release of Renin activate?
2. When does the kidney produce it?
- Renin-Angiotensin System (RAS)
- Drop in blood pressure in the kidneys
- What does the Renin-Angiotensin (RAS) system make?
- And what does that stimulate?
- Angiotensin II
- Aldosterone
If the kidneys detected a drop in BP, what would system is triggered?
Renin-Angiotensin System (RAS)
What is hormone is produced in the heart?
Atrial Natriuretic Peptide (ANP)
What is Aldosterone’s antagonist?
Atrial Natriuretic Peptide (ANP)
The release of Atrial Natriuretic Peptide (ANP) influences what?
Blood pressure. It decreases BP by reabsorbing K+ and secreting Na+ into urine to PEE out.
Ovaries produce what two hormones?
Estrogen and Progesterone
- Testes produce what hormones?
- Which specifically is most important?
Androgens & Testosterone
Thyroxine (T3), Triiodothyronine (T4) and Calcitonin are produced where?
Thyroid
Explain calcitonin’s effect on Calcium Homeostasis
“Puts calcium IN to bone”. Decreases calcium levels in blood
What is the effect of Parathyroid Hormone?
Pulls calcium into the blood by stimulating osteoclasts on the bone.
aka. pulls calcium from bone to correct low calcium blood levels
What is the only hormone that DECREASES blood pressure?
ANP
What hormone imbalance results in exophthalmos (bulging eyes), increased heart rate, increased BP, and heightened metabolic rate ?
Graves disease
aka. Hyperthyroid
What is the major contributing factor to blood viscosity?
Erythrocytes (RBCs)
How many Oxygen can be transported per hemoglobin?
4
What is it called when O2 loads onto hemoglobin in the lungs?
oxyhemoglobin
What is it called when O2 unloads off the hemoglobin into the tissues?
deoxyhemoglobin
What is it called when CO2 loads onto the hemoglobin in tissues?
carbaminohemoglobin
What hormone is produced by the kidney in response to hypoxia/hypoxemia?
Erythropoietin (EPO)
What is the stem cell for ALL blood cells?
Hemocytoblast
What results when a person is not able to produce intrinsic factor, there for cannot absorb B12?
Pernicious anemia
Neutrophils fight against ________.
Bacteria
Eosinophil fight ________.
Parasites
Basophil fight against _____________
Basophil
The three steps of hemostasis
- Vascular spasm
- Platelet Plug formation
- Coagulation
A clot that develops and stays in the blood vessel, causes a blockage, and can result in tissue death
Thrombus
Thrombus floating in blood stream
Embolus
What are the three tonsils called?
- Palatine (back of mouth)
- Pharyngeal (nasopharynx)
- Lingual (posterior tongue)
Where do lymphocytes migrate to arise as T-cells?
Thymus gland
What are the two types of immunity?
Innate/specific and Adaptive/nonspecific
What is your first line of defense in relation to the immune system?
Skin and Mucous membranes
What is your second line of defense in relation to the immune system?
Cells and Chemicals
What are the five cells/chemicals that fall within the innate immune system?
- Natural Killers
- Inflammatory response
- Chemicals that kill pathogens (complement & interferons)
- Faver
- Phagocytes
Aggressive lymphocytes that kill cancer cells, viruses, etc.
Natural Killer Cells