Endocrine and metabolic bone disorders

Question 1

Bone effects in children from vitamin D deficiency

Answer 1

Rickets

• cartilage of epiphysial growth plates and bone effected
• results in skeletal abnormalities and pain, growth retardation and increased fracture risk

Question 2

Bone effects in adults from vitamin D deficiency

Answer 2

Osteomalacia

• after epiphyseal closure, affects bone
• results in skeletal pain, increased fracture risk, proximal myopathy