Endocrine Flashcards
Endocrine glands
o Hypothalmus o Anterior and Poster lobes of pituitary o Thyroid o Parathyroid o Adrenal Cortex o Adrenal Medulla o Gonads o Placenta o Pancreas
hormones
Secreted into the circulation in small amounts and delivered to target tissues, where they produce physiologic responses
Synthesized and secreted by endocrine cells usually found in endocrine glands
Categories of hormones
peptides (amino acids)
Steroids ( cholesterol)
Amines ( Tyrosine)
steroid hormones
- Cortisol
- Aldosterone
- Estradiol and estriol
- Progesterone
- Testosterone
- 1,25-dihydroxychoecalciferol
amine hormones
Catecholamines (Epinephrine, NE, and dopamine) & Thyroid hormones
Regulation of Hormone Secretion
neural mechanism
feedback mechanism
negative feedback
positive feedback
Neural mechanism
Secretion of catecholamines
Preganglionic sympathetic nerves synapse on the adrenal medulla & cause secretion of catecholamines into circulation
Feedback mechanisms
More common
Some element of the physiologic response to a hormone “feeds back” either directly or indirectly on the endocrine gland that secreted the hormone – changing its secretion rate
Negative Feedback
Some feature of hormone action – directly or indirectly – inhibits further secretion of hormone
(self-inhibiting)
Positive Feedback
Uncommon
Some feature of hormone action causes more secretion of the hormone
(self-augmenting)
example of positive feedback
estrogen secreted from the ovaries acts on the anterior pituitary to cause secretion of FSH and LH — and these anterior pituitary hormones cause more estrogen secretion