Endocrine Flashcards
Pituitary gland
produces hormones that regulate growth, metabolism, and reproduction
FSH
follicle stimulating hormone
stimulates growth of gonads
LF
luteinizing hormone
stimulates growth of gonads
ACTH
adrenocorticotropic hormone
stimulates adrenal gland, cortex to grow and be happy
TSH
thyroid stimulating hormone
PRL
prolactin
stimulates mammary glands
GH
growth hormone
stimulates bones and muscles
ADH
antidiuretic hormone
increases reabsorption of water from urine (kidney)
OT
oxytocin function on uterus and mammary glands
neuroendocrine cells
dump hormones into primary plexus
somatotrophs
secrete somatotropin (GH); inducers (GHRH); targets (all body cells); effects (cell growth and division); inhibitors (GHIH(somatostatin), IGFs)
mammotrphs
secrete prolactin (PRL); induced (PRH); effects (mammary gland development and lactation); inhibitors (PIH(dopamine))
corticotrophs
secrete adrenocorticotrophic hormone (ACTH); inducer (CRH); target (adrenal cortex); effect (cortisol release); inhibitor (cortisol)
gonadotrophs
secrete gonadotropins (follicle stimulating hormone (FSH) and luteinizing hormone (LH)); inducer (GnRH); inhibited by ovarian and testicular hormones; effects FSH - stimulates ovarian follicular development and sperm production LH - stimulates ovulation and testosterone production
thyrotrophs
secrete thyroid stimulating hormone (TSH); inducer (TRH); target (thyroid gland); effect (T3 and T4 release); inhibitors (T3 and T4)
antidiuretic hormone (ADH)
inducers (increase blood osmolarity, decreased volume and decreased pressure); targets (kidney collecting ducts); effects (water reabsorption, urine concentration); inhibitors (decrease blood osmolarity, increased volume, and increased pressure; alcohol)
oxytocin (OT)
inducers (infant nursing and crying); targets (uterus and breasts); effects (uterine contractions, milk let-down); inhibitors (Stress, catecholamines (epinephrine and norepinephrine))
thyroid gland
secretes T4 and T3
involved in growth and development and metabolism
secretes calcitonin; decreases blood calcium levels
hypothyroidism (e.g., hashimoto’s thyroiditis, cretinism)
poor mental health and physical function, decreased cold resistance, impaired cognitive development in children
hyperthyroidism (e.g, graves disease)
wasting, nervousness, increased heat production, tachycardia
parathyroid gland
produce parathyroid hormone (PTH); increases blood Ca levels
PTH target cells are in the bone and kidney
adrenal glands
outer adrenal cortex - 90%, inner suprarenal medulla
cortex produces corticosteroids; regulated by ACTH
medulla is regulated by sympathetic nervous system
zona glomerulos
ultimately produces aldosterone - corticol steroid - salt and water balance
zona fasciculata
ultimately produces cortisol (anti inflammatory and stress)