Endocrine Flashcards

1
Q

Pituitary gland

A

produces hormones that regulate growth, metabolism, and reproduction

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2
Q

FSH

A

follicle stimulating hormone

stimulates growth of gonads

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3
Q

LF

A

luteinizing hormone

stimulates growth of gonads

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4
Q

ACTH

A

adrenocorticotropic hormone

stimulates adrenal gland, cortex to grow and be happy

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5
Q

TSH

A

thyroid stimulating hormone

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6
Q

PRL

A

prolactin

stimulates mammary glands

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7
Q

GH

A

growth hormone

stimulates bones and muscles

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8
Q

ADH

A

antidiuretic hormone

increases reabsorption of water from urine (kidney)

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9
Q

OT

A
oxytocin
function on uterus and mammary glands
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10
Q

neuroendocrine cells

A

dump hormones into primary plexus

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11
Q

somatotrophs

A

secrete somatotropin (GH); inducers (GHRH); targets (all body cells); effects (cell growth and division); inhibitors (GHIH(somatostatin), IGFs)

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12
Q

mammotrphs

A

secrete prolactin (PRL); induced (PRH); effects (mammary gland development and lactation); inhibitors (PIH(dopamine))

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13
Q

corticotrophs

A

secrete adrenocorticotrophic hormone (ACTH); inducer (CRH); target (adrenal cortex); effect (cortisol release); inhibitor (cortisol)

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14
Q

gonadotrophs

A
secrete gonadotropins (follicle stimulating hormone (FSH) and luteinizing hormone (LH)); inducer (GnRH); inhibited by ovarian and testicular hormones; effects 
FSH - stimulates ovarian follicular development and sperm production
LH - stimulates ovulation and testosterone production
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15
Q

thyrotrophs

A

secrete thyroid stimulating hormone (TSH); inducer (TRH); target (thyroid gland); effect (T3 and T4 release); inhibitors (T3 and T4)

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16
Q

antidiuretic hormone (ADH)

A

inducers (increase blood osmolarity, decreased volume and decreased pressure); targets (kidney collecting ducts); effects (water reabsorption, urine concentration); inhibitors (decrease blood osmolarity, increased volume, and increased pressure; alcohol)

17
Q

oxytocin (OT)

A

inducers (infant nursing and crying); targets (uterus and breasts); effects (uterine contractions, milk let-down); inhibitors (Stress, catecholamines (epinephrine and norepinephrine))

18
Q

thyroid gland

A

secretes T4 and T3
involved in growth and development and metabolism
secretes calcitonin; decreases blood calcium levels

19
Q

hypothyroidism (e.g., hashimoto’s thyroiditis, cretinism)

A

poor mental health and physical function, decreased cold resistance, impaired cognitive development in children

20
Q

hyperthyroidism (e.g, graves disease)

A

wasting, nervousness, increased heat production, tachycardia

21
Q

parathyroid gland

A

produce parathyroid hormone (PTH); increases blood Ca levels

PTH target cells are in the bone and kidney

22
Q

adrenal glands

A

outer adrenal cortex - 90%, inner suprarenal medulla
cortex produces corticosteroids; regulated by ACTH
medulla is regulated by sympathetic nervous system

23
Q

zona glomerulos

A

ultimately produces aldosterone - corticol steroid - salt and water balance

24
Q

zona fasciculata

A

ultimately produces cortisol (anti inflammatory and stress)

25
Q

zona reticularis

A

DHEA and Androstenedione

26
Q

adrenal insufficiency

A
low cortisol (hypocortisolism)
primary, secondary, tertiary
27
Q

adrenal excess

A
high cortisol (hypercortisolism)
primary, secondary, tertiary
28
Q

Islets of langerhans

A

cellular endocrine units of the predominantly exocrine pancreas
individual cells of islets manufacture and secrete hormones into the surrounding vasculature in a typical endocrine fashion

29
Q

type 1 diabetes

A

insulin dependent
autoimmune disorder targeting islet beta cells
requires insulin injection daily

30
Q

type 2 diabetes

A

non insulin dependent
target cells become resistant to insulin or beta cells do not produce enough insulin (or insulin malfunction)
requires changes in diet and sometimes drugs