Endocrine

Question 1

What is the most common “functioning” pituitary adenoma?

Answer 1

Prolactinoma

Question 2

What is the 2nd most common “functioning” pituitary adenoma?

Answer 2

GH-producing adenoma

Question 3

What accounts for a minority of GH-producing adenomas?

Answer 3

Germline mutation of AIP

Question 4

Which type of disease is Sheehan syndrome?

Answer 4

A Hypopituitarism of the Anterior Pituitary

Question 5

What is “Sheehan syndrome”

Answer 5

Ischemic necrosis of the anterior pituitary

Question 6

What is seen in Posterior Hypopituitarism?

Answer 6

Inability to produce ADH
Diabetes insipidus
Dilute urine, extreme thirst, dehydration

Question 7

Inappropriate ADH syndrome is marked by:

Answer 7

Excess resorption of free water

Hyponatremia, Increased TBW, Cerebral edema, Neurologic dysfunction

Question 8

What are two autoimmune diseases of the thyroid?

Answer 8

Grave’s Disease

Hashimoto Thyroiditis

Question 9

How can one test for Grave’s Disease

Answer 9

Low TSH
High T4
High Iodine-131 uptake
Autoantibody presence

Question 10

Which autoimmune disease of the thyroid is associated with HLA presence?

Answer 10

Grave’s Disease

Question 11

Which autoimmune disease of the thyroid is characterized by a TRIAD of manifestations?

Answer 11

Grave’s Disease

1) Thyrotoxicosis
2) Infiltrative opthalmopathy
3) Infiltrative dermopathy