Endocrine Flashcards
Paracrine
Local effects but not on the cell that secretes the chemicals
Autocrin
Chemicals that exert their effects on the same cells that secrete them
Hormone
Chemical substances secreted by cells into extracellular fluids
Leukotrienes
Signal chemicals involved with inflammation
Prostaglandin
Multiple targets and effects, Dilation or constriction of smooth muscle, Enhance pain
Mechanisms of Hormone Activity
Alter target cell activity Open or Close membrane Ion Channels Stimulate protein synthesis Activate/Deactivate enzymes Stimulates Mitosis
List Non-Polar Hormones
Steroids
Thyroid Hormones
List Polar Hormones
Insulin
Epinephrine
Amino Acid Based (mostly)
Pancreas
List hormones, Actions, What it’s regulated by
Insulin - Lowers blood glucose, regulated by blood glucose
Glucagon - Raises blood glucose, regulated by blood glucose
Adrenal Medulla
Epinephrine and Norepinephrine - Raise blood glucose level; increase metabolic activities;constrict certain blood vesses, regulated by nervous system
Adrenal Cortex
Glucocorticoids - Raise blood glucose level, regulated by ACTH
Mineralocorticoids - Promote reabsorption of Na+ and excretion of K+ in kidneys, regulated by K+ in blood and angiotensin II
Testes
Androgens - Support sperm formation; promote development and maintenance of male secondary sex characteristics, regulated by FSH, LH
Ovaries
Estrogens - Stimulate uterine lining growth; promote development and maintenance of female secondary sex characteristics, regulated by FSH, LH
Progestins - Promote uterine lining growth, regulated by FSH, LH
Pineal Gland
Melatonin - Involved in biological rhythms, regulated by light/dark cycles
3 steps of membrane receptor activity
- Reception
- Transduction
- Response
Hypothalamus
Hormones released from posterior pituitary and hormones that regulate the anterior pituitary
Releasing/Inhibiting hormone
Posterior Pituitary
Oxytocin - Stimulates Contraction of uterus and mammary gland cells, regulated by nervous system
ADH - Promotes retention of water by kidneys, regulated by water/salt balance
Anterior Pituitary
GH - Stimulated growth Prolactin - Stimulates milk production FSH - Stimulates production of ova/sperm LH - Stimulates ovaries/testes TSH - Stimulates thyroid gland ACTH - Stimulates adrenal cortex to secrete glucocorticoids All regulated by Hypothalamus
Thyroid Gland
T3/T4 - Stimulate and maintain metabolic processes, regulated by TSH
Calcitonin - Lowers blood Ca++, regulated by Ca++ in blood
Parathyroid Glands
PTH - Raises blood Ca++, regulated by Ca++ in blood
Humoral Function
Reaction by changing blood levels of critical ion/nutrients
Hormonal Function
Releasing hormones in response to a hormone
What does the Diencephalon Do?
Autonomic control center Regulates cardiac/smooth/gland secretion Control Homeostasis Thermostat Regulate hunger/thirst Hormones for posterior pituitary Releasing hormones for anterior pituitary
Adenohypophysis
Anterior Pituitary
Neurohypophysis
Posterior Pituitary
Infundibulum
Pituitary Stalk
Somatotropin
Produced by somatotrophs in anterior pituitary
Growth Hormone
Promotes protein systhesis
Promotes use of fats for fuels
Stimulates epiphyseal plate of long bones
Promotes increased muscle mass