Endocrine Flashcards

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1
Q

Homeostasis

A

The ability to keep your internal environment within normal/stable working limits.

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2
Q

Homeostasis examples

A

body temp, BP, blood sugar, sodium, potassium

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3
Q

What stimulates insulin secretion?

A

Sugar/glucose

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4
Q

How does insulin travel to its target cells?

A

It travels thru blood

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5
Q

How do cells receive the insulin signal?

A

Insulin attaches to its receptors

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6
Q

After peaking, what causes insulin secretion to decrease?

A

Decrease in blood glucose

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7
Q

Patient 1 cannot produce insulin. How would this condition affect blood glucose homeostasis?

A

High blood glucose

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8
Q

Why do hormones target some cells but not others?

A

It must have a specific receptor

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9
Q

What could go wrong with endocrine signaling?

A
  1. damage to the gland
  2. damage to the receptor
  3. another chemical mimics the hormone and attaches to the recceptor
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10
Q

How are endocrine organs stimulated?

A
  1. Humoral
  2. Neural
  3. Hormonal
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11
Q

Humoral

A

blood carries the hormone and stimulates the gland

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12
Q

Neural

A

Sympathetic nervous system- Neurons stimulate the gland

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13
Q

Hormonal

A

Hormone to hormone from one gland to another gland

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14
Q

Neurohypophysis is also called

A

AKA- Posterior Pituitary gland

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15
Q

Posterior Pituitary gland releases what hormones?

A

releases 2 hormones- ADH- (anti diuretic)

OT (oxytocin)

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16
Q

Adenohypophysis is also called

A

AKA- Anterior Pituitary gland

17
Q

Anterior Pituitary gland produces what hormones?

A

Produces ACTH, FSH, LH, GH, TSH, MSH

18
Q

Hypothalamus produces what hormones?

A

Produces CRH, GHRH, GHIH, GnRH, TRH, PRH, PIH

19
Q

Follicle cells

A

Produce thyroid hormone (TH) - thyrogobulin

20
Q

colloid

A

stores thyrogobulin

21
Q

Parafollicular cells

A

Produces calcitonin

22
Q

Why do you think a number of major endocrine pathways utilize the H-P axis?

A
  1. Nervous and endocrine systems merge at the H-P axis.

2. Feedback to the nervous system…pass on to the pituitary keeping checks and balances

23
Q

H- TRH

P- TSH

A

Target organ - Thyroid

24
Q

H- GHRH

P- GH

A

Target organ - liver and all body

25
Q

H-CRH

P- ACTH

A

Target organ- Adrenal cortex

26
Q

H-GnRH

P- FSH/LS

A

Target organ - Ovaries & testes

27
Q

H- PRH

P - PRL

A

Target organ- Breast

28
Q

ADH

A

Target organ - kidneys

29
Q

OT (oxytocin)

A

Target organ- Breast & Uterus

30
Q

Hypothyroid symptoms

A

weight gain, slow metabolism, tired, low blood pressure, low heart rate, sleepy

31
Q

Hashimoto’s disease

A

autoimmune disease where thyroid gland is gradually destroyed. Treated with Thyroxine

32
Q

Endemic goiter

A

enlarged thyroid gland due to dietary iodine.

33
Q

Cretinism

A

hypothyroidism in infants due to iodine deficiency.

34
Q

Hyperthyroid symptoms

A

increased heart rate, high blood pressure, weight loss

35
Q

Grave’s disease

A

autoimmune disease in which auto-antibodies stimulate the TSH receptor

36
Q

Adrenal glands

A

Located on top of kidneys. Hormones from adrenal glands help maintain homeostasis when the body is stressed.

37
Q

Adrenal Cortex

A

produces:
1. Glucocorticoids (Cortisol)
2. Aldosterone
3. Androgens

38
Q

Adrenal Medulla

A

Produces Epinephrine and norepinephrine in response to neural stimulation- fight or flight

39
Q

Pancreas

A

Is an endocrine & exocrine gland. It regulates blood glucose levels thru secretion of insulin & glucagon.