Endocrine Flashcards

1
Q

What do hormones control?

A

– Reproduction
– Growth and development
– Mobilization of body defenses
– Maintenance of much of homeostasis
– Regulation of metabolism

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2
Q

Hormones are classified chemically as what?

A

Proteins, peptides, amines, also known as proteins, fat, and steroids

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3
Q

When hormones arouse cells or alter cellular activity what can happen? (5 options)

A
  1. Change plasma membrane permeability or membrane
    potential by opening or closing ion channels
  2. Activate or inactivate enzymes
  3. Stimulate or inhibit cell division
  4. Promote or inhibit secretion of a product
  5. Turn on or turn off transcription of certain genes
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4
Q

What two mechanisms do hormones act by?

A
  1. Direct gene activation
  2. Second-messenger system
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5
Q

Explain direct gene activation

A
  1. Steroid hormone diffuses through the plasma
    membrane of target cells
  2. Once inside the cell, the hormone enters the nucleus
  3. Then, the hormone binds to a specific protein within
    the nucleus
  4. Hormone-receptor complex binds to specific sites on
    the cell’s DNA
  5. Certain genes are activated to transcribe messenger
    RNA
  6. New proteins are synthesized
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6
Q

Explain second-messenger system

A
  1. Hormone (first messenger) binds to a receptor
    protein on the plasma membrane
  2. Activated receptor sets off a series of reactions that
    activates an enzyme
  3. Enzyme catalyzes a reaction that produces a
    second-messenger molecule (such as cyclic AMP,
    known as cAMP)
  4. Second messenger molecule oversees additional
    intracellular changes to promote a specific response
    in the target cell
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7
Q

What are hormone levels in the blood maintained by?

A

Negative feedback systems

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8
Q

What are the groups of stimuli that activate endocrine glands?

A
  1. Hormonal
  2. Humoral
  3. Neural
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9
Q

What is a hormonal stimuli?

A

Endocrine organs are activated by other hormones

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10
Q

What is a humoral stimuli?

A

Changing blood levels of certain ions and nutrients stimulate hormone release.

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11
Q

What is a neural stimuli?

A

Nerve fibers stimulate hormone release.

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12
Q

Name the MAJOR endocrine organs.

A

Hypothalamus
* Pituitary gland
* Pineal gland
* Thyroid gland
* Parathyroid glands
* Thymus
* Adrenal glands
* Pancreas
* Gonads (testes and ovaries)

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13
Q

What is the master endocrine gland and why?

A

Pituitary gland, because it controls activities of so many other endocrine glands

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14
Q

Other organs that are generally nonendocrine in function but also secrete hormones are…

A

– Stomach
– Small intestine
– Kidneys
– Heart
– placenta

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15
Q

What is Calcitonin?

A

Decreases blood calcium by causing
deposition of calcium into bone from thyroid gland

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16
Q

What is thyroid hormone?

A

Major metabolic hormone, controls rate of oxidation of glucose for body heat and formation of ATP from the thyroid gland

17
Q

What is Insulin?

A

Released from the pancreas when blood glucose levels are high to increase uptake and metabolism of glucose.

18
Q

What is Glucagon?

A

Released from pancreas when blood glucose levels are low, stimulates liver to release glucose to the blood

19
Q

What is thymosin?

A

-Released from the Thymus
– Matures some types of white blood cells
– Important in developing the immune system

20
Q
A