Endocrine

Question 1

Celiac disease can cause osteomalacia how

Answer 1

malabsorption of vitamin D in the small intestines from intraepithelial lymphocytosis causes hypocalcemia (which can be the lower limit of normal) and secondary osteomalacia. (bone softening due to prolonged vitamin D deficiency)

patients can also have secondary hyperparathyroidism and hypophosphatemia

Question 2

Hereditary hypophosphatemic rickets

Answer 2

X linked dominant inability of the renal tubule to reabsorb phosphate

Question 3

Vitamin D deficiency rickets

Answer 3

deficiency in 1a- hydroxylase, cant convert 25 hydroxy-vitamin D to 1,25-dihydoxy-vitamin D

Question 4

Osteodystrophy (Albright)

Answer 4

psuedohypoparathyroidism where the kidneys cannot respond to parthyroid hormone and causes hypocalcemia

short stature, development delay, brachydactyyly, round facies and developmental delay