Endocrine Flashcards
management of adrenal crisis
hydrocortisone 100mg IV load x1 followed bay 50mg IV Q6H
IV hydration
Identification of precipitating cause
Education on sick day rules + suggest medialert bracelet
Definition of adrenal incidentaloma
A clinically unapparent adrenal mass >1 cm in diameter detected during imaging performed for reasons other than for suspected adrenal disease
Screening Indicated for ALL adrenal incidentalomas
hypercortisolism or MACS with 1mg Dexamethasone suppression test
Pheochromocytoma with metanephrines
Electrolytes for hyperaldosteronism screening (HypoK)
Aldosterone Renin Ratio only if HypoK and HTN
testing to differentiate between primary and secondary hypogonadism in males
FSH + LH Low or inappropriately normal - SECONDARY
FSH + LH High - PRIMARY
Causes of secondary hypogonadism
pituitary adenoma
hemochromatosis
hyperprolactinoma
Anabolic steroids
Obesity
opioids
T2DM
Medications causing Hypoglycemia
Indomethacin
Quinine
glucagon (during endoscopy)
Pentamidine
Gatifloxacin
Cibenzoline
Lithium
ACE/ARB
Levofloxacin (Rare but Common RC answer)
beta antagonists
Septra
Whipple’s triad for hypoglycemia
Symptoms of hypoglycemia
Low plasma glucose when symptoms present
Resolution of symptoms with treatment
Expected lab values in primary hyperparathyroidism
Serum Calcium: high
Urine Calcium: high
Serum PTH: high
Serum PO4: Low
Expected lab values in tertiary hyperparathyroidism
Serum Calcium: High
Urine Calcium: high
Serum PTH: high
Serum PO4: high
Expected lab values in pseudo hypo-parathyroidism
Serum Calcium: Low
Urine Calcium: Variable
Serum PTH: High
Serum PO4: High
Expected lab values in FHH
Serum Calcium: High
Urine Calcium: Low
Serum PTH: High
Serum PO4: Low
Expected lab values in vitamin D Deficiency
Serum Calcium: Low
Urine Calcium: High/ Normal
Serum PTH: High
Serum PO4: Low
Expected lab values in Vitamin D excess
Serum Calcium: High
Urine Calcium: high
Serum PTH: Low
Serum PO4: High
Expected Lab values in PTHrP
Serum Calcium: High
urine Calcium: High
Serum PTH: Low
Serum PO4: Low
High risk features of thyroid nodules
Microcalcifications - highest specificity on USS for Ca
Hypoechoic
irregular margins
taller than wide
Extrathyroidal extension
Peripheral (rim) calcifications
Lymphadenopathy
>20% increase in 2 dimensions