Endocrine Flashcards

1
Q

management of adrenal crisis

A

hydrocortisone 100mg IV load x1 followed bay 50mg IV Q6H
IV hydration
Identification of precipitating cause
Education on sick day rules + suggest medialert bracelet

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2
Q

Definition of adrenal incidentaloma

A

A clinically unapparent adrenal mass >1 cm in diameter detected during imaging performed for reasons other than for suspected adrenal disease

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3
Q

Screening Indicated for ALL adrenal incidentalomas

A

hypercortisolism or MACS with 1mg Dexamethasone suppression test
Pheochromocytoma with metanephrines
Electrolytes for hyperaldosteronism screening (HypoK)
Aldosterone Renin Ratio only if HypoK and HTN

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4
Q

testing to differentiate between primary and secondary hypogonadism in males

A

FSH + LH Low or inappropriately normal - SECONDARY
FSH + LH High - PRIMARY

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5
Q

Causes of secondary hypogonadism

A

pituitary adenoma
hemochromatosis
hyperprolactinoma
Anabolic steroids
Obesity
opioids
T2DM

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6
Q

Medications causing Hypoglycemia

A

Indomethacin
Quinine
glucagon (during endoscopy)
Pentamidine
Gatifloxacin
Cibenzoline
Lithium
ACE/ARB
Levofloxacin (Rare but Common RC answer)
beta antagonists
Septra

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7
Q

Whipple’s triad for hypoglycemia

A

Symptoms of hypoglycemia
Low plasma glucose when symptoms present
Resolution of symptoms with treatment

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8
Q

Expected lab values in primary hyperparathyroidism

A

Serum Calcium: high
Urine Calcium: high
Serum PTH: high
Serum PO4: Low

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9
Q

Expected lab values in tertiary hyperparathyroidism

A

Serum Calcium: High
Urine Calcium: high
Serum PTH: high
Serum PO4: high

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10
Q

Expected lab values in pseudo hypo-parathyroidism

A

Serum Calcium: Low
Urine Calcium: Variable
Serum PTH: High
Serum PO4: High

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11
Q

Expected lab values in FHH

A

Serum Calcium: High
Urine Calcium: Low
Serum PTH: High
Serum PO4: Low

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12
Q

Expected lab values in vitamin D Deficiency

A

Serum Calcium: Low
Urine Calcium: High/ Normal
Serum PTH: High
Serum PO4: Low

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13
Q

Expected lab values in Vitamin D excess

A

Serum Calcium: High
Urine Calcium: high
Serum PTH: Low
Serum PO4: High

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14
Q

Expected Lab values in PTHrP

A

Serum Calcium: High
urine Calcium: High
Serum PTH: Low
Serum PO4: Low

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15
Q

High risk features of thyroid nodules

A

Microcalcifications - highest specificity on USS for Ca
Hypoechoic
irregular margins
taller than wide
Extrathyroidal extension
Peripheral (rim) calcifications
Lymphadenopathy
>20% increase in 2 dimensions

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