Endo Pastest Flashcards
What are the ionic abnormalities in Cushing’s?
Hypernatremia, Hypokalemia
What are the ionic abnormalities in Hypopituitarism?
Hyponatremia, Hyperkalemia
What are the ionic abnormalities in Primary Hyperparathyroidism?
Hypercalcemia, Hypophosphatemia, Normal PTH, High ALP
Why is there normal PTH in Primary Hyperparathyroidism?
This is because it is due to a parathyroid adenoma, therefore you get high PTH. In normal metabolism, a high Ca suppresses PTH, therefore w/ the hypercalcemia you expect to see low PTH but is inappropriately normal.
What is the pathophysiology of Secondary Hypoparathyroidism?
The main cause is hypocalcemia (due to vitamin D deficiency, or renal failure). This leads to PT hypertrophy and excretion, which leads to High PTH.
What are the ionic abnormalities in secondary hyperparathyroidism?
Hypocalcemia, Hyperphosphatemia & High PTH (inappropriately normal)
Ionic abnormalities in Addison’s Disease?
Hyponatremia, Hyperkalemia
Symptoms of Addison’s?
Fatigue, Postural Hypotension, Hyperpigmentation of mucosal surfaces, Muscle Weakness
What condition can occur due to subarachnoid Hemorrhage?
SIADH
What is the classic triad of MEN 2A?
Medullary Thyroid Carcinoma, Primary Hyperparathyroidism, Pheochromocytoma
What is the classic triad of MEN 1?
Pituitary, Parathyroid & Pancreatic
What is the classic triad of MEN 2B?
Pheochromocytoma, Medullary Thyroid cancer, Marfanoid Habitus/Mucosal Neuromas
What condition is associated with Addisonian Crisis?
This can be seen with RA that is controlled with oral prednisolone.
S&S of Addisonian Crisis?
Hyponatremia, Hyperkalemia, Hypoglycemia.
What is a side effect of GLP-1 RA?
Delayed gastric emptying
