Endo Emergencies Flashcards
What are the three things needed for rapid Dx of DKA
D - BM >11
K - Ketones >3
A - acidosis ph<7.3
What are investigations necessary for DKA
Capillary ketones, glucose Assess damage (BLOODS: CBG, lab glucose, ketones, FBC, U&E, BC, WCC, CRP -- ABG) ECG Consider CXR, urine dip Find cause
What can trigger a DKA
V - MI Infection Trauma AI Metabilic - insulin missed, alcohol Inflammation - pancrewattis Neoplastic Drugs: insluin missed
Where may you have to transfer a DKA patient if severe
ITU /HDU
How do you manage DKA
Fluids Insulin Potassium Dextrose VTE prophylaxis (as dehydratred)
How much fluid do you give for DKA
500ml bolus over 15mins if SBP <90»_space; then 1L/HOUR
if SBP normal: start giving 1L/h immediately NaCò
How much insulin do you give for DKA
Add 50U of insulin to 50ml NaCl
infuse. at rate of 0.1U/kg/hr
Fixed rate IV insulin infusion
+ patient’s normal long acting SC insulin
How muck K+ do you give in DKA
Run 40mmol KCl in NaCl even if K+ is normal
(not in first bag through - only when K+ between 3.5 and 5.5)
This is because insulin can cause hypokalaemia
How much dextrose do you give in DKA and when
10% dextrose when BM<14, 100ml/h
What are common complications of DKA
Cerebral oedema
aspiration pneumonia
VTE
electrolyte imbalance
How does insulin cause hypokalaemia
it drives potassium into skeletal and hepatic cells
What is HHS
Hyperglycaemic hyperosmolar state
What kinds of patients does HHS occur in, and what are RF
Patients with T2DM
Usually if non-adherent to medications, infection, steroids…
What are sx of HHS
longer history than DKA (1 week) polyuria polydipsia decreased consciousness severe dehydration, volume depletion
How do you manage HHS
LMWH (high VTE risk)
Start IV fluids - 0.9% 1L NaCl over 2h
Start fixed rate insulin infusion 0.05U/kg/h only if glucose stops falling or if ketonuria 2+
THEN:
Slow rehydration over 48 hours - at half the rate of DKA fluids
Replace K+ when UO increases
What investigations must you get in a patient with suspected poisoning
ALL UNCONSCIOUS patients: glucose, paracetamol, salicylate levels
FBC, U&E, LFT, INR, ABG, ECG
How do you reverse benzo
Flumazenil
How do you reverse opiate
naxolone
how to you reverse paracetamol
N-acetylcysteine
How do you reverse. aspirin
sodium bicarb
How do you assess Burn Size
Rule of 9 Rule (“Lung and Browder”)
The palm is 1% of body area
Why is it important to estimate burn size
So you can estimate inflamm response and fluid shift > it may require fluid resus
> 10-15% TBSA will require fluid resus
Why is it important to assess thickness. of burn?
It influences healing time and scarring
What are the degrees of burns and can you describe them
1st degree: mild erythema
2nd degree: painful erythema
3rd degree: do not blister, no sensation, look leathery/brown/black