End-Stage Renal Disease, and Transplant

Question 1

What are the leading causes of ESRD?

Answer 1

• Diabetes

- HTN

Question 2

What are the S/S of ESRD?

Answer 2

• ↓ U/o, or no urine output
• generalized pruritus
• Easy bruising/bleeding
• N/V/D
• Malaise/Fatigue/HA
• Lethargy

Question 3

What are some potential outcomes of Uremic Syndrome?

Answer 3

1. Uremic Encephalopathy – confusion, stupor, coma,
2. Severe Fatigue
3. Anorexia, N/V, weight loss
4. Pericarditis – inflammation & excess fluid in sac around heart
5. Pleural effusion – SOB due to fluid around lungs

Question 4

What are indications for Hemodialysis?

Answer 4

1. Control of electrolytes (hyperkalemia)
2. Control of volume status
3. Control of uremia
4. Control of acidosis
5. GFR estimation <10-15mls/min

Question 5

What are the S/E of Hemodialysis?

Answer 5

• Rapid loss of plasma solute concentration and PH in addition to the ultrafiltration of H20.
• hypotension, muscle cramps, nausea, vomiting, headaches, seizures