End-Stage Disease Process Flashcards
Pleural effusion: occurs
when there is a discrepancy between the secretion and absorption of fluid in the pleural space
Pleural effusion: secretion rates
increased and/or fluid absorption becomes restsricted, causing excessive fliud to collect
Pleural effusion: onset
can be slow or rapid
Pleural effusion: patient present with ?
dyspnea
Pleural effusion: dyspnea
results from the collapse of the lung due to increased pleural fluid pressure inability to expand lung leads to complaints of dyspnea
Pleural effusion: as affected area increases
dyspnea distress increases orthopnea ( breathlessness in the recumbent position) tachypnea anorexia malaise and fatigue
Pleural effusion: pt c/o
dry, nonproductive cough aching, heaviness, or dull pain in chest
Pleural effusion: treatment
palliative and symtomatic in nature dependent on: surrounding circumstances overall patient condition proximity to death
Pericardial effusion: definition
accumulation of fluid or tumor cells within the pericardial sac
Pericardial effusion: affect
nearly 20% of patients with lung cancer during advanced stages of disease patienbts with
Pericardial effusion: associated with
breast cancer leukemia lymphoma
Pericardial effusion: prognosis
poor
Pericardial effusion: caused by
cancerous cells treatments used for malignancies nonmalignant causes
Pericardial effusion: identifying causes
pericarditis congestive heart failure uremia myocardial infarction autoimmune disease infections hypothyroidism renal and hepatic failure
Pericardial effusion: clinical signs dependent on
amount of fluid how quickly it accumulates general health of cardiac tissue
Pericardial effusion: most common symptom
dyspnea patient may be unable to speak more than one word with each breath
Pericardial effusion: symptoms
dyspnea chest heaviness dry cough generalized weakness tachycardia
Pericardial effusion: tachycardia
body tries to compensate for the reduced cardiac output
Hemoptysis: definition
expectoration of blood from lower respiratory tract
Hemoptysis: occcurs
in patients with advanced cancer because of metastasis or infection
Hemoptysis: cause
advanced cancer with metastasis infections bronchitis
Hemoptysis: initial assessment
distinguish from gastrointestinal and nasopharyngeal bleeding
Hemoptysis: signs and symptoms
cough dyspnea wheezing chest pain fever night sweats weight loss
Hemoptysis: severity
determined by amount of blood produced within a 24 hour period
Hemoptysis: mild
production of less than 15-20 ml of blood within 24 hours
Hemoptysis: moderate
expectoration of greater than 20 ml, but less than 200 ml
Hemoptysis: massive
200 to 600 ml within 24 hour period occurs in fewer than 5% of cases, but is life-threatening and associated with 85% mortality rate
Hemoptysis: primary risk
asphyxiation from blood clots in airway
Superior vena cava syndrome: definition
result of a partial occlusion of the superior vena cava
Superior vena cava syndrome: results
decreased blood flow from the head and neck to the right atrium
Superior vena cava syndrome: cause
cancerous growths
Superior vena cava syndrome: considered
emergency condition
Superior vena cava syndrome: symptoms
headache facial edema hoarseness dyspnea swollen arms
Superior vena cava syndrome: rapid onset
loss of circulation can be life-threatening
Superior vena cava syndrome: onset
rapid or acute
Superior vena cava syndrome: subtle signs
swelling in morning hours increasing discomfort with bending forward or stooping
Superior vena cava syndrome: common complaine
dyspnea
Superior vena cava syndrome: physical findings
vein distention in neck and chest ruddy complexion or cyanosis tachypnea stridor orthopnea hoarseness nasal stuffiness periorbital and conjunctival edema
Superior vena cava syndrome: progressing symptoms
mental status changes
Superior vena cava syndrome: mental status changes
progressing from a stupor, coma, and seizures until time of death
Hypercalcemia: definition
overabundance of ionized calcium in the blood
Hypercalcemia: occurs
in up to 10% of cancer patients
Hypercalcemia: highest rates of occurrence
breast cancer multiple myeloma
Hypercalcemia: causes
hyperparathyroidism lithium therapy vitamin D milk-alkali syndrome
Hypercalcemia: untreated
50% mortality rate
Hypercalcemia: symptoms depend on
amount of excess calcium
Hypercalcemia: untreated
irreversible renal damage coma death
Hypercalcemia: presenting complaints
fatigue lethargy nausea polyuria confusion
Hypercalcemia:left unchecked
combination of nausea and polyuria can again increase concentrations of calcium in blood through dehydration
Hypercalcemia: symptoms
vomiting anorexia constipation
Hypercalcemia:electrocardiogram
show evidence of a shortened QT interval and possible arrhythmias
Hypercalcemia: assessments
avoid attaching symptoms to other disease processes in the already ill patient
Hypercalcemia: treatment to lower calcium levels
hydration with saline bisphosphonates diuretics glucocorticoids
Death pronouncement: prior
to time of death, a plan should be in place for who will be contacted when death occurs, regardless of location
Death pronouncement: procedures
vary between state to state
Death pronouncement: nurses
vary by state
Death pronouncement: inpatient setting
organizational policy should be follwed
Death pronouncement: hospice setting
nurse makes a visit for patient assessment
Death pronouncement: nurse visit
patient assessment verbally conveys absence of vital signs and pertinent information to physician contacts funeral home or mortuary may be necessary to contact police or coroner
Death pronouncement: contact coroner
if circumstances of death were unusual, associated with a traumatic event, or occurred within 24 hours of hospital admission
Central ascites: cause
results from compressoin of the portal venous or lymphatic system compression from tumor invasion
Central ascites: process
decrease in pressure as a result of limited limited protein intake and the catabolic state associated with cancer
Peripheral ascites: cause
results from deposits of tumor cells on the parietal or visceral peritoneum blockage occurs at this level rather than in the liver parenchyma
Peripheral ascites: presence of macrophages
increases capillary permeability and contributes to increasing fluid retention
Mixed type ascites: definition
combination of both peripheral and central ascites
Types of ascites
central peripheral mixed chylous malignant malignant
Chylous malignant: defintion
occurs when cancer cells invade the retroperitoneal space, causing lymph flow obstruction for the lymph nodes or pancreas
Malignant ascites
generally has poor prognosis
Malignant ascites: tumor cells
make difficult to reduce fluid accumulation
Ascites: cancer associated with
ovarian endometrial breast colon gastric pancreatic
Ascites: less common sources
mesothelioma non-Hodgkin lymphoma prostate cancer
AIDS dementia complex: cause
exact cause unknown
AIDS dementia complex: result
primary result of disease process itself
AIDS dementia complex: theory of cause
HIV infection stimulates an invasion of macrophages in brain (microglia) These release cytokines that directly damage nervous tissue by disrupting neurotransmitter functions cause encephalopathy
AIDS dementia complex: affects
15% of all AIDS patients
AIDS dementia complex: prognosis
poor disease not reversible
AIDS dementia complex: retrovirals
can delay onset
AIDS dementia complex: children
CNS HIV infection in children tends to have a more dramatic and pronounced effect than that in adults
AIDS dementia complex: Characterized by
gradual memory loss decreased concentration decreased cognition mood disorders
AIDS dementia complex: physical symptoms
ataxia incontinence seizures
Amyotrophic lateral sclerosis: defintion
rapidly progressing degenerative neuromuscular disease with an unknown origin