Encephalopathy

Question 1

CADASIL

Answer 1

Young pr with stroke, seizure, psychiatric symptoms

Anterior temporal lobe + External capsule/Insular cortex

Sparing of cerebral cortex

Question 2

Korsakoff syn

Answer 2

Same as wernicke

Dorsal thalamus, mamillary body, PAG

Question 3

Wilson

Answer 3

Midbrain - spares red nuc
Pons
Double panda
Putamen
Caudate nucleus

Dwi restriction in striatum
T1 hypo OR hyper - same as chro hepato

Question 4

CO poisoning

Answer 4

Basal ganglia bilateral - Medial Globus Pallidus specifically

Question 5

NBIA - PKAN

Answer 5

T2 hypo at globus pallidus and substantia nigra pars reticulata

Question 6

Neuro Behcet

Answer 6

Meningoencephalitis, venous thrombosis, Basal Ganglia and thalamus
Also brainstem, WM, spinal cord

Question 7

Methanol and cyanide

Answer 7

Putamen necrosis

Question 8

Japanese encephalitis

Answer 8

BG and thalamus
Also cortex, SN, Red Nuc, Pons, Cerebellum

Question 9

Osmotic demyelination

Answer 9

BG and Thalamus
Pons - trident, bat wing

Question 10

Leigh disease

Answer 10

BG Thalamus
Also PAG, Cerebral peduncle

Question 11

Hypoglycemia

Answer 11

BG, Insula, Post limb of IC, Parieto Occ Cortex
SPARING OF thalami, subcortical WM, Deep WM, Cerebellum

Boomerang sign of CLOCC
DWI restriction

Question 12

Hypertension

Answer 12

PRES
HTNsive - BG, Brain stem, convexial SAH like RCVS, ENHANCEMENT, DWI restriction

Question 13

Hyperglycemia

Answer 13

Chronic - subcort and PV WM
Acute - HHH - T1 hyper in BG SPARING thalami
HONK - PO Cortex and CC splenium

Question 14

Hepatic Enceph

Answer 14

Acute - Insula, Cingulate Gyrus, BG maybe thalamus SPARING occipital WM and cerb cortex
Chronic - T1 hyper medial GP