Dementia

Question 1

Parkinson brain

Answer 1

Gen atrophy
Thinning substantia niagra + pars compacta
DAT - low uptake in post putamen

Question 2

Lewy body dementia mri brain

Answer 2

Fluctuant symptoms
Parkinsonian features
Visual halu
NO MEMORY LOSS
Generalised cort atrophy but SPARES HIPPOCAMPUS
OCCIPITAL INVOLVEMENT (spared in alz)
HMPAO - low perf in TEMPOROPARIETAL CORTEX + PRESERVATION OF metabolism in MID POSTERIOR CINGULATE

Question 3

Alzheimer brain

Answer 3

FDG > HMPAO
Low uptake in PRECUNEUS, POSTERIOR CINGULATE, FRONTAL AND TEMPORAL with
Classic SPARING of SENSORIMOTOR CORTEX AND BASAL GANGLIA, OCCIPITAL CORTEX

Question 4

Pick’s disease

Answer 4

FRONTO TEMPORAL LOBE affected WITH
ANTERIOR CINGULATE gyrus
SPARING of Posterior cingulate and Precuneus