Emetics

Question 1

What might you use first-line for an anti-emetic

Answer 1

Cyclizine (antihistamine) is good at treating nausea arising from a number of conditions

Question 2

When would cyclizine be contraindicated

Answer 2

Heart failure as causes peripheral oedema

Question 3

When would you use metacloperamide (dopamine receptor antagonist)

Answer 3

nausea associated with GI disorders as stimulates gastric emptying.
use for heart failure instead of cyclising

Question 4

when wouldn’t you use metoclopramide

Answer 4

contraindicated in parkinsons and bowel obstruction

Question 5

When would you use ondansetron (5HT3 receptor antgonist)

Answer 5

very good for chemotherapy nausea

post operative nausea

Question 6

when would you use haloperidol [unlicensed] to relieve nausea

Answer 6

palliative care - good sedating effect

Question 7

when would you use domperidone (dopamine receptor antagonist) for nausea

Answer 7

Parkinson’s disease as does not act centrally in low doses, good at relieving nausea caused by dopaminergic drugs

Question 8

what might you use for chemotherapy induced nausea

Answer 8

ondansetron
dexamethasone
prochlorperazine (first gen anti-psychotic)