EMERGENT ALS Drugs Flashcards
ACETAMINOPHEN
Action
Analgesic and Antipyretic
ACETAMINOPHEN
Indications/Contraindications
Indications: Fever >100.4 / Minor injury or pain
Contraindications: Altered mentation, Lethargic, Dysphagia, Liver failure
ACETAMINOPHEN
Dose
15mg/kg (1 gram Maximum)
Every six hours as needed
Onset: 15-20 mins
ASPRIN
Action
Interferes with platelet aggregation and is known as an anti-platelet medication.
ASPRIN
Indications
- Myocardial infarction patients reduce the risk of death in patients with previous infarction
- Unstable angina
- Cardiac related chest pain
ASPRIN
Contraindications
- Known hypersensitivity to this medication
* Recent history of gastric or duodenal ulcers
ASPRIN
Dose
324 mg (4 baby asprin or 1 adult strength
ADENOSINE
Action
It slows conduction through the AV node- It is useful in blocking re-
entrant pathways in supraventricular tachycardia.
ADENOSINE
Indications
Treatment of PSVT (including Wolfe-Parkinson-White Syndrome)
ADENOSINE
Contraindications
- Second or third-degree AV blocks
- Sick sinus syndrome
- History of WPW
- Hypersensitivity to this medication
ADENOSINE
Dose
Adult: [20 mL Syringe]
• 6 mg rapid IV Push
• Repeat dose of 12 mg rapidly IVP if no conversion after 3 minutes
Pediatric: [10 mL Syringe]
• 0.1mg/kg IV or IO push
• If no response, double the original dose and repeat once in three minutes
ALBUTEROL
Action
Albuterol is a sympathomimetic bronchodilator. It acts selectively on beta 2 receptors to relax bronchial smooth muscle.
ALBUTEROL
Indications
- Hyperkalemia
- Bronchospasm secondary to asthma or exacerbation of COPD
Albuterol
Contraindications
- Hypersensitivity to albuterol
* Tachycardia
ALBUTEROL
Dose
Neb 1 - 2.5 —5.0 mg via nebulizer, with 02 set to 6 liter/min Neb 2 - 10mg over 1 hour Maximum dose 20mg
AMIODARONE
Action
Amiodarone is an antiarrhythmic medication; calcium, potassium and sodium channel blocker; negative chronotropic, negative dromotropic, and vasodilator. Its vasodilatory effects can decrease cardiac workload and as a result, decrease myocardial oxygen consumption.
AMIODARONE
Indications
- VF/Pulseless VT
- VT with a pulse
AMIODARONE
Contraindications
- Hypersensitivity to the drug
- Cardiogenic shock
- Sinus bradycardia
- High degree AV block
AMIODARONE
Side Effects
- Bradycardia
- AV block
- Nausea
- Vasodilatation and hypotension
AMIODARONE
Dose
Adult:
Cardiac Arrest - VF/ pulseless VT
300 mg IV push followed by an immediate 20-30 ml flush
If refractory, consider a repeat dose in 3-5 minutes, of 150 mg IV push in (3 ml, 1 vial) followed by an immediate 20„30 ml flush
Ventricular ectopy:
For V Tach with pulse and unstable PSVT administer150 mg slow IV over 10 minutes. (Mix 3 ml (150 mg) in 100 ml D5W)
Pediatric:
Cardiac Arrest VF Pulseless VT
5 mg/kg, IV / 10
Repeat up to 15 mg/kg
Max dose 300 mg
ATROPINE
Action
Effects include dilation of the pupils, relaxation of the bronchioles, decreased gastric motility and increased heart rate. It produces both positive chronotropic and positive dromotropic effects.
ATROPINE
Indications
- Symptomatic bradycardia
- Organophosphate poisoning
- Pre-medication for R-S-I intubation in pediatric patients
ATROPINE
Contraindications
- narrow angle glaucoma
- myasthenia gravies
- Tachycardia
- Newborns
- heart transplant patients
ATROPINE
Dose
Adults: 1 IV • 0.5- 1.0 mg IV push, rapidly every 3 5 minutes 2 IV - 2 - 5 mg every 3 to 5 minutes - MAXIMUM dose is 0 .04 mg/kg
Pediatric:
• 0.02 mg/kg IV push
- MAXIMUM single dose of 0.5 mg in children and 1.0 mg in adolescents
Note
- Atropine may be given via E-T- tube, at 2 – 2.5 times the IV dose
- Organophosphate poisoning may require large doses (5-10 mg) for symptom relief
CALCIUM CHLORIDE
Action
Calcium Chloride is an essential electrolyte for functional integrity of the nervous and muscular system, cardiac contractility and coagulation of blood.
CALCIUM CHLORIDE
Indications
- Beta blocker overdose
- hyperkalemia
- calcium channel blocker toxicity
- cardiac resuscitation (questionable value)
CALCIUM CHLORIDE
Contraindications
- Ventricular fibrillation during arrest
- Hypercalcemia
- Digitalis toxicity
CALCIUM CHLORIDE
Dose
Adult 1 & 2 IV: 1 - 2 grams over 5 mins q 10-20 min 3 IV: 1 gram slow over 2 mins Pediatric 1 IV: Not Indicated 2 IV: 20mg/kg over 5-10 mins 3 IV: 20mg/kg over 2 mins
MAXIMUM q dose: 1 gram
Dextrose
Action
Dextrose stimulates the transient take calcium by cells, Especially in muscle tissue, lowering serum test
Dextrose
Indications
- hypoglycemia
- Hyperkalemia (must be used in combination with insulin)
Dextrose
Contraindications
-Hyperglycemia
Dextrose
(Dose)
Adult
1 IV: 12.5 - 25 grams of D50 or D25 slow
2 IV: 25 grams of D50 or D25 followed by…..
Infusion: 0.5g/kg/hr, titrate glucose to 100-200 mg/dL
Pediatric
1 IV: 0.5 - 1g/kg of D25 over 15-30 min
Infusion: 0.5 - 1 g/kg of D25 over 15-30 mins
Diltiazem
Action
Inhibits calcium ions from entering the slow channels of the vascular smooth muscle and myocardium during depolarization. It produces relaxation of the coronary vascular smooth muscle/coronary vasodilation.
Diltiazem
(indications)
- atrial fibrillation
- atrial flutter
- SVT
Diltiazem
Contraindications
–2nd or 3rd heart block (Without a pacemaker)
– Atrial fib/flutter with accessory bypass tract
-WPW or short PR syndrome
– Sick sinus syndrome (without a pacemaker)
- ventricular tachycardia
Diltiazem
Dose
Adult
IV: 0.25 mg/kg over 2 min; repeat 0.35 mg/kg q 15 min
Infusion: 5-15 mg/hr; Titrate to affect
MAXIMUM 15mg/hr
Pediatric
IV: 0.25 mg/kg over 5 min; repeat q 15 min
Infusion: 0.05-0.15 mg/kg/hr; titrate to affect
MAXIMUM q dose 20mg|Total 15mg/hr
Diphenhydramine
Action
It is an anti-histamine that competes for the H1 receptor sites on effector cells in the G.I. tract, blood vessels, and respiratory tract. Sedative affects are also seen.
Diphenhydramine
Indications
- Allergic reactions/Anaphylaxis/Behavioral emergencies/Dystonic reactions
- Anti-emetic/Motion Sickness
Diphenhydramine
Contraindications
-Acute asthma
–Nursing mothers
-Patient taking MAO inhibitors
Diphenhydramine
Dose
ADULT 1 IV/IM 25-50 mg q 6 hours 2 IV 10-50 mg q 6 hours MAXIMUM q dose: 50 mg MAXIMUM Total: 300mg
PEDIATRIC 1 IV/IM 1-2 mg/kg q 6 hours 2 IV 1 mg/kg q 6 hours MAXIMUM q dose: 50 mg MAXIMUM Total dose: 150
Epinephrine
(Action)
Stimulates Alpha1 & Beta2 receptors. Positive inotropic, Chronotropic, dromotropic effects.
Epinephrine
Indications/Contraindications
 Indications 1. Allergic reactions 2. Bradycardia 3. Hypotension/Cardiogenic shock 4. Cardiac arrest Contraindications -None
Epinephrine
(Adult dose)
1IM: 0.3-0.5 mg (1mg/mL) q 15 min
1NEB: 3 mg (1mg/mL) for STRIDOR
2 & 3 Infusion: 2mcg/min; titrate to effect
4IV: 1 mg (0.1 mg/mL) q 3 - 5 mins
MAXIMUM
Infusion: 10mcg/min
Epinephrine
(Pedi Dose)
1IM: 0.01 mg/kg (1mg/mL) q 15 min
1NEB: 3 mg (1mg/mL) for STRIDOR
2 & 4IV: 0.01 mg/kg (0.1mg/mL) q 3 - 5 min
2 & 3 Infusion: 0.01 mcg/kg/min, titrate to effect
Etomidate
Action
Sedative, with no analgesic or muscle relaxing effects
Etomidate
Indication
-Rapid Sequence intubation
Etomidate
Contraindication
- Adrenal Insufficiency
- Suspected Sepsis
- Pregnancy/Lactation
- SBP <90 mmHg
Etomidate
Adult Dose
IV: 0.3 - 0.5 mg/kg
Etomidate
Pedi dose
IV: 0.2 - 0.4 mg/kg
Fentanyl
Action
It binds with opioid receptors and increases pain threshold; produces CNS depression
Fentanyl
(Indications)
- Pain management
- Post intubation management
- Rapid sequence intubation
Fentanyl
Contraindications
- Myasthenia gravis
- Pregnancy or Lactation
Fentanyl
Adult Dose
- IV/IM 0.25-1mcg/kg slow q 5-10 minutes
- IV 0.25-3mcg/kg q 10 minutes
- -Infusion 1-2mcg/kg/hr - IV 1-3mcg/kg over 30-60 seconds
MAXIMUM
q dose: 100mcg
Total: 300mcg
Fentanyl
Pediatric Dose
- IV/IM 1-2 mcg/kg slow q 10-15 minutes
- IV 0.25-3mcg/kg q 10 minutes
- -Infusion 0.5-2mcg/kg/hr - IV 2-3mcg/kg over 30-60 seconds
MAXIMUM
q dose: 50mcg
Total: 200mcg
Haloperidol
Action
It is an antipsychotic that depresses the central nervous system
Haloperidol
Indications
- Acute psychotic disorder
2. Nausea and/or Vomiting
Haloperidol
Adult dose
- IM 2.5-5mg
MAXIMUM
q dose: 5mg
Haloperidol
Contraindications
- CNS depression/Comatose
- Prolonged QT interval
- Zofran [8mg] administered in the last 24 hours
Instant Glucose
Adult Dose
PO: 15 grams
Instant Glucose
Pediatric Dose
PO: 0.2 g/kg
Ketamine
Action
Produces a catacleptic-like state in which the patient is dissociated from the surrounding environment
Ketamine
Indications
- Agitation/Behavioral Emergencies
- Pain Mangagement
- Rapid Sequence Inubation/Awake Intubation
- Sedation/Post Intubation Management
Ketamine
Contraindications
- Cushings Reflex
- Ocular trauma
- Severe Hypertension
Ketamine
Adult ONLY Dose