Emergency Medicine: Pretest Flashcards
Which medication is typically used to treat supraventricular tachycardias?
Adenosine
This is an ultrashort-acting AV nodal blocking agent. Because it is so fast-acting it must be delivered through a large vein with a rapid intravenous fluid bolus. In addition to adenosine, maneuvers that increase vagal tone have been shown to slow conduction through the AV node. Some of these maneuvers include carotid sinus massage, Valsalva maneuver, and facial immersion in cold water.
Large R waves and inverted T waves in leads V1-V3 are indicative of what?
Right heart strain
Dysuria in young men is almost always because of what?
Urethritis
This is commonly sexually transmitted.
What are the Ranson criteria and what are they used for?
The Ranson criteria are used for predicting mortality rates in patients with pancreatitis. The presence of more than 3 criteria equals 1% mortality, while the presence of 6 or more criteria approaches 100%.
Ranson criteria at admission:
- Age > 55
- WBC > 16,000
- Glucose > 200
- LDH > 350
- AST greater than 250
Ranson criteria within 48 hours of admission:
- Hematocrit fall > 10%
- BUN rise > 5
- Serum calcium less than 8
- Arterial PO2 < 60
- Base deficit > 4
- Fluid sequestration > 6L
A 50% chance of passage of a renal stone occurs when the stone is what size?
4-6mm
6mm stones pas 10% of the time.
What are the 3 zones of the neck?
- Zone I: Extends superiorly from the sternal notch and clavicles to the cricoid cartilage
- Zone II: Area between the cricoid cartilage and the angle of the mandible
- Zone III: Extends from the angle of the mandible to the base of the skull
Zone II injuries are taken directly to the operating room for surgical exploration.
What condition is described as a polymicrobial necrotizing fasciitis of the perineal subcutaneous tissue that originates from the skin, urethra, or rectum?
Fournier syndrome
What is the single most common drug that leads to death in overdose?
Acetaminophen
What is the treatment for isoniazid-induced seizures?
Pyridoxine (Vitamin B6)
What are the potential causes of anion gap metabolic acidosis?
- Methanol, metformin
- Uremia
- Diabetic ketoacidosis
- Paraldehyde
- Iron, isoniazid
- Lactate
- Ethylene glycol, ethanol
- Salicylate
This can be remembered by the pneumonic MUDPILES.
Profound hyperglycemia without ketonuria is suggestive of what diagnosis?
Nonketotic hyperosmolar crisis (NKHC)
This syndrome is more common in type 2 diabetes mellitus. Patients are profoundly dehydrated because of osmotic diuresis. The mainstay of NKHC therapy consists of replacing fluid losses.
Postpartum eclampsia needs to be managed with what?
Magnesium sulfate
Hypertension, bradycardia, and respiratory depression make up what triad?
Cushing reflex
This is observed in 1/3 of patients with a potentially lethal increase in intracranial pressure.
What is the gold standard diagnostic approach to mesenteric ischemia?
Angiography
Unlike any other diagnostic tool, it is capable of both diagnosing and treating the problem.
Any patient presenting to the emergency department in the second or third trimester of pregnancy with bleeding should have ultrasound performed before pelvic examination to rule out what?
Placenta previa
Placenta previa is a contraindication to digital examination of the cervix, as placental trauma from the examination itself can lead to prfuse vaginal bleeding.
What is the best method of diagnosing corneal abrasions?
Slit-lamp examination by observing fluorescein uptake in the area of the defect
Patients wearing contact lenses should be treated with topical antibiotics with antipseudomonal coverage.
What is the mainstay of treatment for pericarditis?
Anti-inflammatory medications (I.E. NSAIDs)
An echocardiogram should be performed to rule out a pericardial effusion and tamponade.
What 3 medications should be given to a patient with an anaphylactice reaction to an allergen?
- Epinephrine
- Antihistamine (I.E. diphenhydramine, ranitidine)
- Corticosteroid (I.E. methylprednisolone)
Antihistamines block the action of the circulating histamines at target tissue receptors. Corticosteroids have an onset of action of 4-6 hours after administration, and therefore are of limited value in the acute setting, but should be given since giving them early may blunt to biphasic reaction of anaphylaxis.
What drug can be given to decrease runs of torsades des pointes?
Magnesium sulfate
Altered mental status, hyperthermia, and muscle rigidity make up the classic triad for what condition?
Neuroleptic malignant syndrome (NMS)
This is a rare, but fatal reaction commonly associated with the use of antipsychotics. The cornerstone of treatment is supportive care with rapid cooling, fluid and electrolyte repletion, and monitoring. Dantrolene, a nonspecific skeletal muscle relaxant, generally used in the treatment of malignant hyperthermia, is also effective for NMS.
What is the best method of diagnosing benign positional vertigo?
Dix-Hallpike maneuver
The maneuver involves having the patient go from sitting to a supine position with eyes open and head rotated to the affected side. The test is positive if the maneuver reproduces vertigo and the patient exhibits latent rotary nystagmus.
What intracompartmental pressure measured with a Stryker device is considered diagnostic of compartment syndrome?
> 30mmHg
The presence of a pulse does not rule out compartment syndrome. The only way to diagnose compartment syndrome is to measure intracompartmental pressure with a Stryker device.
Cardiac contusion most commonly occurs in what part of the heart?
Right ventricle
It is the most anterior aspect of the heart and closest to the sternum.
What is the fastest method of lowering intracranial pressure?
Hyperventilation
The onset of action is within 30 seconds.
Which street drug can cause significant hyponatremia?
3,4-Methylenedioxymethamphetamine (MDMA)
It is a potent stimulus for serotonin release which results in the excessive release of vasopressin (ADH). This combined with large free-water intake (increased thirst), and increased sodium loss from physical exertion (dancing) result in hyponatremia.
All patients with chest pain and shortness of breath should recieve what test?
Electrocardiogram (ECG)
It is a quick, noninvasive test that often provides substantive information.
What symptoms are characteristic of the anticholinergic toxidrome?
Delirium, mumbling speech, tachycardia, elevated temperature, flushed face, dry mucous membranes and skin, dilated pupils, and hypoactive bowel sounds.
This can be remembered by the phrase “Blind as a bat (mydriasis), red as a beet (flushed skin), hot as a hare (hyperthermia due to lack of sweating), dry as a bone (dry mucous membranes), and mad as a hatter (mental status change)”.
What is the appropriate management of a patient who presents after exposing an eye to superglue?
Application of large amounts of erythromycin gel in the eye
This lubricates the eye and prevents the abrasive effect.
What is the first-line therapy for patients with stable supraventricular tachycardia?
Adenosine
It is safe and effective and has a short half-life. It blocks conduction at the atrioventricular node leading to a brief period of asystole, which can be very disconcerting to those recieving or administering the medication.
Which medication is notorious for causeing seizures that are refractory to standard therapy?
Isoniazid
Pyridoxine (vitamin B6) is the treatment of choice.
Different degrees of paralysis and loss of pain and temperature sensation in the setting of intack position, touch, and vibratory sensation are characteristic of what?
Anterior cord syndrome
The hallmark is the preservation of the posterior columns, maintaining position, touch, and vibratory sensation.
What has proven effective for both prophylaxis and treatment of acute mountain sickness?
Acetazolamide
Supplemental oxygen and a descent of 1500 to 3000 feet will reverse high-altitude sickness in most cases. Nausea and vomiting can also be treated symptomatically. Hyperbaric oxygen is indicated in severe cases.
What must happen for “flail chest” to occur?
Fracture of 3 or more adjacent ribs at two points
What is the most common cause of arrest in children?
Respiratory
What is the most useful diagnostic test in a patient suspected to have a spinal epidural abscess?
Magnetic resonance imaging (MRI)
Respiratory depression with apnea, interrupted by periods of agitation and combativeness (especially following attempts at intubation) are a distinctive feature of intoxication with which substance?
Gamma-hdroxybutyrate (GHB)
GHB is a natural neurotransmitter that induces sleep. It has been sold as a muscle builder (sleep increases release of growth hormone), a diet aid, and a sleep aid. Patients with GHB overdose generally have a decreased level of consciousness. In contrast to other sedative/hynotic overdoses, the level of consciousness tends to fluctuate quickly between agitation and depression.
Which organ is most commonly injured as a result of blunt abdominal trauma?
Spleen
In approximately 66% of cases, it is the only damaged intraperitoneal organ. The liver is the second most commonly injured organ.
Brown-Sequard syndrome (hemisection of the spinal cord) results in what symptoms?
- Ipsilateral motor paralysis
- Contralateral loss of pain and temperature
What is the treatment for post-lumbar puncture headache?
A blood patch
This is done by injecting an aliquot of the patient’s blood in a sterile fashion just external to the dura mater at the same interspace where the LP occurred.
Which toxic alcohol does not cause metabolic acidosis?
Isopropyl alcohol
This is because it is metabolized to acetone, a ketone, not an acid. Isopropyl alcohol intoxication is often remembered by “ketosis without acidosis.” Another unique finding is the presence of “pseudo renal failure” or isolated false elevation of creatinine with a normal BUN. This results from interference of acetone and acetoacetate by the colorimetric method used to measure the creatinine level.
How does the Prehn sign help differentiate between testicular torsion and epididymitis?
The pain from epididymitis is relieved by physically lifting the testicle, but the pain from testicular torsion is not
What is the initial treatment for acute pancreatitis?
Supportive: bowel rest, fluid resuscitation, and analgesia
90% of patients recover without complications. Surgery is reserved for complications of alcoholic pancreatitis, such as pseudocysts, phlegmons, and abscesses.
How does Central cord syndrome present?
Greater neurological deficits in the upper extremities compared to the lower extremities
In addition, patients with central cord syndrome usually have decreased rectal sphincter tone and patchy, unpredictable sensory deficits.
1-2 weeks of fever, localized pain in the back, and progressive weakness is suggestive of what diagnosis?
Spinal epidural abscess
An elevated white blood cell count is also commonly seen. Magnetic resonance imaging is the most useful diagnostic test.
What are the two main therapeutic agents in treating hepatic encephalopathy?
Lactulose and neomycin
Serum ammonia level is usually elevated in hepatic encephalopaty. Lactulose is a poorly absorbed sugar metabolized by colonic bacteria that traps ammonia and helps excrete it in the stool. Neomycin is a poorly absorbed aminoglycoside that is believed to act by reducing colonic bacteria responsible for producing ammonia.
Which medication is the most effective and most rapid means of reducing preload in a patient with congestive heart failure?
Nitroglycerin
Nitrates decrease myocardial preload and, to a lesser extent, afterload. Nitrates increase venous capacitance, including venous pooling, which decreases preload and myocardial oxygen demand. It is most beneficial when the patient who presents with congestive heart failure is also hypertensive. It is administered sublingually, intravenously, or transdermally. By contrast, Sodium Nitroprusside is is a mixed venous and arteriolar dilator; it reduces both pre- and afterload. It can be used in patients with acute pulmonary edema, but is typically reserved for individuals with a systolic blood pressure greater than 100 mmHg who fail to respond to adequate doses of standard preload reducers.
What causes miliaria rubra (heat rash)?
Sweat gland blockage and staphylococcal infection
What cause of chest pain occurs at rest and follows a circadian pattern, with most episodes occurring in the early hours of the morning?
Prinzmetal (Variant) angina
This is caused by focal coronary artery vasospasm.
What is the first test that should be used to diagnose ovarian torsion?
Doppler ultrasound
CT scan may be necessary if the doppler study is equivocal.
What is the most common cause of painful rectal bleeding in the first year of life and in adults?
Anal fissures
The following signs/symptoms are characteristic of which diagnosis?
- Eye pain
- Fever
- impaired eye motility
- Decreased visual acuity
- Proptosis
Orbital cellulitis
Staphylococcus aureus and Haemophilus influenzae are common etiologies. Mucormycosis must be considered in diabetics and immunocompromised patients.
What is the preferred treatment for an ST-elevation myocardial infarction?
Primary percutaneous intervention (I.E. angioplasty or stent)
It has been shown to improve long-term mortality over thrombolytic therapy.
What kind of crystals are found in pseudogout?
Calcium pyrophosphate crystals
The synovial fluid will reveal rhomboid-shaped crystals that are weakly positively birefringent under polarized light.
What is the best method of managing intussusception?
Air enema
This is both diagnostic and therapeutic.
In addition to peaked T-waves, hyperkalemia can cause what two electrocardiogram (ECG) changes?
- Loss of P waves
- Widening of the QRS complex
Eventually the tracing assumes a sine-wave pattern, followed by ventricular fibrillation or asystole.
Supraventricular tachycardia that is refractory to vagal maneuvers should be treated with what?
Adenosine
This is a very short-acting AV nodal blocking medication.
The following signs/symptoms are characteristic of which diagnosis?
- Eye pain
- Blepharospasm (any abnormal contraction or twitch of the eyelid)
- Tearing
- Photophobia
- Foreign body sensation in eye
- Injected eye
- Punctuate lesions on corneal examination
- Decreased visual acuity
Ultraviolet keratitis (snow blindness)
This is essentially a radiation burn when an individual comes in close contact with an ultraviolet-ray-containing light source (Sun lamp, tanning bed, high altitude). Patients usually present 6-10 hours after exposure.
Myxedema coma is a life-threatening complication of which condition?
Hypothyroidism
Mortality in myxedema coma approaches 20-50% even with appropriate management.
What is the best method of diagnosing multiple sclerosis (MS)?
Magnetic resonance imaging (MRI)
Demyelinating MS lesions are often well demonstrated on MRI but cannot be visualized on computed tomography (CT).
What is the mainstay of diabetic ketoacidosis management?
Aggressive fluid resuscitation and insulin therapy
Which kind of fracture occurs when the head is thrown into extreme hyperextension because of abrupt deceleration?
Hangman’s fracture (traumatic spondylolysis of C2)
This is characterized by bilateral fractures of the pedicles. Today the most common cause of a hangman’s fracture is the result of head-on automobile collisions.
What disease presents as a prodrome of 1-2 days of mild headache and myalgias, followed by high fever, chills, multiple rigors, and the following associated symptoms?
- Pulmonary: Cough, dyspnea, chest pain, hemoptysis
- Gastrointestinal: Nausea, vomiting, diarrhea, anorexia
- Neurological: Headache, altered mental status
Legionnaires disease
This is caused by Legoinella pneumophila, an intracellular organsim that lives in aquatic environments.
What is the most common pathogen responsible for causing necrotizing otitis externa?
Pseudomonas aeruginosa
This is an uncommon complication of otitis externa that occurs primarily in adult diabetics and other immunocompromised individuals. It is associated with a high mortality rate.
Which 5 drugs can be effectively administered via endotracheal tube?
- Naloxone
- Atropine
- Versed
- Epinephrine
- Lidocaine
This is remembered by the mnemonic NAVEL.
A 90% chance of passage of a renal stone occurs when the stone is what size?
<4cm
4-6mm stones pass 50% of the time. >6mm stones pas 10% of the time.
A transvaginal ultrasound can typically identify a gestational sac when the beta-hCG level is greater than what level?
1000mIU/mL
It can identify the yolk sac when the beta-hCG level is greater than 2500 mIU/mL.
Fracture of the neck of the 5th metacarpal is known as what?
Boxer’s fracture
It is one of the most common fractures of the hand and usually occurs from a direct impact to the hand (I.E. a punch with a closed fist).
What is the treatment of choice for miliaria rubra (heat rash)?
The antibiotic Chlorhexidine
This should be used in the acute phase. Salicylic acid may also be used to assist in desquamation but should not be used on large areas because of possible salicylate intoxication.
What should be given to contact lens-wearing patients with corneal abrasions?
Antipseudomonal medication (I.E. Tobramycin or fluoroquinolone drops)
It is important to distinguish corneal abrasions from corneal ulcers. Ulcers are deeper infections of the cornea that develop from corneal epithelial defects (I.E. abrasions). Contact lens wearers are also at high risk for corneal ulcers. The hallmark of a corneal ulcer is a shaggy, white infiltrate within the corneal epithelial defect.
What is the hallmark of beta-blocker toxicity?
- Bradycardia
- Hypotension
- Cold extremities
- Low blood sugar
Onset of toxicity is usually within 4 hours of ingestion. Management consists of fluid resuscitation and atropine. Patients with significant toxicity should recieve glucagon.
A fundoscopic examination that reveals a macular cherry-red spot with a pale retina and less pronounced arteries is diagnostic of what condition?
Central retinal artery occlusion
This is commonly caused by emboli, thrombi, vasculitis, or trauma. Treatment aims to dislodge the clot from the main artery to one of its branches and includes digital massage, vasodilation, and lowering intraocular pressure.
What causes Horner syndrome?
Interrupted sympathetic nerve supply to the eye
Unilateral findings of ptosis, miosis, and anhidrosis are seen.
When should blood products be administered in a trauma patient?
When vital signs only transiently improve or remain unstable despite resuscitation with 2-3 L of crystalloid fluid
If there is obvious major blood loss and the patient is unstable, blood transfusion should be started concomitantly with crystalloid administration.
The following findings are consistent with which diagnosis?
- Muscle weakness
- Hyporeflexia
- Intestinal ileus
- Respiratory paralysis
- Electrocardiogram (ECG) changes: Flattened T waves, presence of U waves, and prolonged QT and PR intervals
Hypokalemia
Potassium deficiency results in hyperpolarization of the cell membrane.
Transverse fracture of the distal radial metaphysis, which is dorsally displaced and angulated is called what?
Colles fracture
This is the most common wrist fracture seen in adults.