Emergency Med Flashcards

1
Q

What GCS or below do we worry about airway compromise?

A

8 or below

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2
Q

What is the toxic dose of paracetamol?

A

75mg/kg

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3
Q

What bloods should be done at 4 hours post ingestion in paracetamol OD?

A
VBG
INR
U&Es
LFTs
FBC
Paracetamol level
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4
Q

How long is the standard course of NAC?

A

21 hours

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5
Q

What 3 criteria do the bloods need to meet post NAC?

A

INR is 1.3 or less AND
ALT is less than two times the upper limit of normal AND
ALT is not more than double the admission measurement

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6
Q

What to do if a pt on warfarin is actively bleeding?

A

Stop warfarin
Give 5mg IV Vit K
IV prothrombin complex concentrate (octaplex)

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7
Q

What does Geriatric Admission Profile (GAPS) include?

A

U&E, FBC, LFT, glucose, CRP, calcium, B12 & folate, ferritin, iron and transferrin, TFT, vitamin D

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8
Q

Bamford stroke classification for TACS?

A
Unilateral weakness (and/or sensory deficit) of the face, arm and leg
Homonymous hemianopia
Higher cerebral dysfunction (dysphasia, visuospatial disorder)
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9
Q

Bamford stroke classification for PACS?

A

2 of 3 symptoms:
Unilateral weakness (and/or sensory deficit) of the face, arm and leg
Homonymous hemianopia
Higher cerebral dysfunction (dysphasia, visuospatial disorder)

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10
Q

What is a lacunar stroke?

A

Purely motor or sensory?

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11
Q

Mx of HTN in in the acute management of ischaemic stroke?

A
Avoid tx unless any of the following:
hypertensive encephalopathy
hypertensive nephropathy
hypertensive cardiac failure/myocardial infarction
aortic dissection
pre-eclampsia/eclampsia
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12
Q

Causes of VF arrests?

A

Electrolyte abnormalities (hyperkalaemia, hypokalaemia, hypocalcaemia)
Toxins (particularly TCA od)
Hypothermia
Less commonly the other causes of cardiac arrest

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13
Q

What rhythm is seen in cardiac arrest?

A

PEA

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14
Q

What should be administered in cardiac arrest with non-shockable rhythm?

A

IV adrenaline

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15
Q

5Ds of Charcot’s foot?

A
Density change (areas of lucency and sclerosis)
Destruction
Debris (loose bodies and bone fragments)
Distension (joint effusion)
Dislocation (e.g. metacarpophalangeal joints)
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16
Q

Gas gangrene abx?

A

Tazocin + clindamycin

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17
Q

Tx for orthostatic hypotension?

A

Fludrocortisone

Midodrine

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18
Q

What temp increase should we aim for in hypothermia?

A

1 degree rise per hour

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19
Q

What formula should be used for burns victims fluid requirement in first 24 hrs?

A

Parkland Formula
Fluid required in 1st 24 hr = 4ml x patients weight in kg x % burn
Half should be given in first 8 hours and remainder over 16 hours

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20
Q

When to catheterise burns patient?

A

Patients with burns >20% TBSA or intubated

Patients with perineal burns or 15-19% TBSA catheterisation should be considered

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21
Q

When to refer to burns unit?

A

Burns > 10 % TBSA in an Adult
Burns > 5 % TBSA in a Child
Full thickness burns > 5% TBSA
Burns of face, hands, feet, perineum, genitalia, and major joints
Circumferential burns
Chemical or electrical burns
Burns in the presence of major trauma or significant co-morbidity
Burns in the very young patient, or the elderly patient
Burns in a pregnant patient
Suspicion of Non-Accidental Injury

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22
Q

First aid for minor burns?

A

Hold under cool running water for 20mins

Wrap in cling film

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23
Q

What layers do superficial, partial and full thickness burns affect?

A

Superficial - epidermis
Partial thickness - dermis
Full thickness - underlying subcutaneous tissue

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24
Q

What should you do with blistered areas of a burn?

A

De-roof, dress with non-adherent dressing and review in 48 hours

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25
Q

Which types of anaesthesia can cause malignant hyperthermia?

A

Volatile anaesthetic agents

Suxamethonium

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26
Q

CIs to lidocaine Tx?

A

SAN disease and all forms of AV block

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27
Q

How long does lidocaine take to work and wear off?

A

Few mins

Lasts 1-2 hours

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28
Q

MOA of lidocaine?

A

Local anaesthetics act on the smaller C fibres, which transmit pain and temperature sensation, before the larger A fibres, which transmit touch and power

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29
Q

Causes of prolonged QTc? (TIMMES)

A

Toxins: drugs including anti-arrhythmics, anti-psychotics, TCAs, macrolides
Inherited: congenital long QT syndromes such as Romano-Ward and Jervell and Lange-Nielson syndromes.
Ischaemia
Myocarditis
Mitral valve prolapse
Electrolyte abnormalities, such as hypokalaemia and hypocalcaemia
Subarachnoid Haemorrhage

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30
Q

Mx of DKA in hour 1 in adults?

A

A to E
1L 0.9% saline over 1 hour (if SBP <90 add STAT bolus 500ml in 15 mins)
Fixed rate insulin infusion (0.1 units/kg/hr) AFTER commencing fluid

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31
Q

What needs to be checked hourly in DKA?

A

Blood/capillary glucose
Blood/capillary ketones
Observations including GCS
AND continuous ECG

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32
Q

Fluid resuscitation in DKA in hours 2-12?

A

If K+ <5.5mmol/L add KCl

1L 0.9% saline + 40mmol KCl over 2 hours then
1L 0.9% saline + 40mmol KCl over 2 hours again then
1L 0.9% saline + 40mmol KCl over 4 hours then
1L 0.9% saline + 40mmol KCl over 4 hours again then
1L 0.9% saline + 40mmol KCl over 6 hours

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33
Q

Until when do you continue fixed rate insulin in DKA?

A

Blood ketones <0.3mmol/L AND
pH >7.3 AND
Bicarbonate >18mmol/L

34
Q

Mx of DKA in hours 12-24?

A

Aim to have normal biochemical parameters
If patient unable to eat and drink then start sliding scale insulin
If able to eat and drink then restart subcutaneous insulin regimen - this will need some crossover with IV insulin.

35
Q

Mx of HHS?

A

Fluid resuscitation
Insulin at 0.05 units/kg/hour
VTE prophylaxis

36
Q

Fluid resuscitation in HHS?

A
Fluid of choice is 0.9% saline:
1L over 1-2 hours
1L (+KCl) over 2-4 hours
1L (+KCl) over 4-6 hours
1L (+KCl) over 6-8 hours
1L (+KCl) over 8-10 hours
37
Q

What score is used prior to endoscopy in patients with an upper GI bleed?

A

Glasgow-Blatchford score

Any score >0 suggests medical intervention needed

38
Q

What score is used after endoscopy in patients with an upper GI bleed?
What is it used to estimate?

A

Rockall score

Used to estimate the risk of re-bleeding and the risk of mortality

39
Q

Define AKI

A

increase in serum creatinine of 26 μmol/L within 48 hours
increase in serum creatinine ≥1.5 times above baseline value within 1 week
urine output of <0.5 ml/kg/hr for > 6 consecutive hours

40
Q

antidote for anti-freeze?

A

Fomepizole

41
Q

Damage to which vessels causes extradural haemorrhage?

A

Middle meningeal vessels

42
Q

Damage to which vessels causes subdural haemorrhage?

A

Bridging veins

43
Q

drug-induced pancreatitis causes? FATSHEEP

A
Furosemide
Azathioprine/Asparaginase
Thiazides/Tetracycline
Statins/Sulfonamides/Sodium Valproate
Hydrochlorothiazide
Estrogens
Ethanol
Protease inhibitors and NRTIs
44
Q

Contraindications to thrombolysis in MI? AGAINST

A
Aortic Dissection
GI bleed
Allergic reaction
Iatrogenic: recent surgery
Neurological disease: recent stroke (within 3 months), malignancy
Severe HTN (>200/120)
Trauma, including recent CPR
45
Q

What common SE can doxycycline cause?

A

Oesophagitis

46
Q

4 adverse signs of tachycardia?

A

Shock
Sycope
Heart failure
Myocardial ischaemia

47
Q

When can you immediately safely cardiovert in AF?

A

No adverse signs

Onset <48 hours

48
Q

How long do patients need anticoagulation before and after cardioversion in AF?

A

3 weeks before

4 weeks after

49
Q

Which meds are CI in WPW?

A

Digoxin

Verapamil

50
Q

What carboxyhaemoglobin concentration is diagnostic of carbon monoxide poisoning?

A

> 20%

51
Q

Beck’s triad of cardiac tamponade?

A

Raised JVP
Hypotension
Muffled heart sounds

52
Q

What is Kussmaul’s sign?

A

Rise in JVP with inspiration

53
Q

What is pulsus paradoxus?

A

Drop in SBP of about 15mmHg with inspiration

54
Q

Aspirin od blood gas findings?

A

Initially respiratory alkalosis

Later metabolic acidosis

55
Q

Features of unstable angina

A

Chest pain at rest or minimal exertion lasting >15 minutes
ECG changes (new ST-depression or T wave inversion)
NO rise in troponin: no myocardial necrosis

56
Q

Features of NSTEMI

A

Chest pain at rest or minimal exertion lasting >15 minutes
ECG changes (new ST-depression of T wave inversion)
Rise in troponin: myocardial necrosis

57
Q

Features of STEMI

A

Chest pain at rest or minimal exertion, lasting >15 minutes
ECG changes (new ST-elevation or left bundle branch block)
Rise in troponin: myocardial necrosis

58
Q

Tx of bradycardia with HISS?

A
Atropine 500mcg IV
Can repeat up to max of 3mg
Isoprenaline 5mcg/min IV
Adrenaline 2-10mcg/min IV
or transcutaneous pacing
59
Q

RFs for acute closed angle glaucoma?

A

Female
Asian
Use of antimuscarinics

60
Q

Tx of acute closed angle glaucoma?

A

IV Acetazolamide and a topical beta-blocker such as Timolol

61
Q

Causes of VT?

A

Electrolyte abnormalities such as hypokalaemia and hypomagnesaemia
Structural heart disease including Myocardial infarction and HOCM
Drugs that cause QT prolongation e.g. clarithromycin, erythromycin
Inherited channelopathies e.g. Romano-Ward syndrome, Brugada syndrome

62
Q

Occlusion of the LAD puts you at increased risk of what?

A

Rupture of interventricular septum

63
Q

What times should mast cell tryptase be measured?

A

Initially
4hrs
12hrs

64
Q

What would you expect to find with an optic neuritis?

A

RAPD

A relatively dilated pupil on the affected side when a torch light is swung towards it

65
Q

Clinical features of central retinal vein occlusion?

A

sudden painless loss of vision

stormy sunset on fundoscopy

66
Q

Clinical features of central retinal artery occlusion?

A

sudden painless loss of vision over a few seconds

pale retina and cherry red spot at macula on fundoscopy

67
Q

Clinical features of Ischaemic optic neuropathy?

A

sudden onset monocular vision loss and colour blindness
RAPD o/e
fundoscopy - optic disc swelling in the acute phase or a pale optic disc in the chronic phase that suggests optic atrophy

68
Q

Clinical features of Retinal detachment?

A

floaters and flashes followed by a ‘curtain falling over’ their vision
pale-grey area of retina ballooning forward on fundoscopy

69
Q

Clinical features of Vitreous haemorrhage?

A

If minor, patients complain of floaters, if severe, patients complain of painless loss of vision
Common in diabetics
Retina hard to view on fundoscopy

70
Q

Clinical features of optic neuritis?

A

Painful loss of vision over hours to days
Pain on moving eyes
‘red desaturation’
Common in MS

71
Q

What to do if a pt has an anaphylactoid reaction to NAC?

A

Stop infusion

Give 10mg IV Chlorphenamine

72
Q

universal donor of fresh frozen plasma?

A

AB RhD negative blood

73
Q

When to discharge in anaphylaxis after symptom resolution?

A

Minimum 2 hours:
1 dose of adrenaline

Minimum 6 hours:
2 doses adrenaline
Previous biphasic response

Minimum 12 hours:
>2 doses adrenaline
severe asthma
ongoing reaction possible
patient presents late at night
when A&E access difficult
74
Q

What to give in potential tetanus exposure and unclear vaccine hx?

A

booster vaccine + immunoglobulin

75
Q

King’s College Hospital criteria for liver transplantation (paracetamol liver failure)?

A

Arterial pH < 7.3, 24 hours after ingestion

or all of the following:
prothrombin time > 100 seconds
creatinine > 300 µmol/l
grade III or IV encephalopathy

76
Q

Indications for thoracotomy in haemothorax?

A

> 1.5L blood initially or losses of >200ml per hour for >2 hours

77
Q

3 things usually given in acute variceal bleed?

A

Blood products
Terlipressin
Empirical abx: Ceftriaxone

78
Q

When to offer platelet transfusions?

A

platelet count of <30 x 10^9 with clinically significant bleeding
platelet count < 100 x 10^9 with severe bleeding or bleeding at critical sites, such as CNS

79
Q

Mx of epistaxis?

A
  1. Pinch the cartilaginous (soft) area of the nose firmly for 20mins
  2. Cautery if bleeding point visible
  3. Packing (rapid rhino)
  4. Sphenopalatine ligation in theatre
80
Q

Flail chest mx?

A

Analgesia

Respiratory support - consider PPV