Emergency Anesthesia Flashcards
What are the 3 classes of sedatives most commonly used in the emergency setting?
Benzos, alpha 2s, and phenothiazines (+ opioids)
What are some pros of using a phenothiazine (such as ace) for sedation?
- Reliable sedation
- may increase threshold for arryhthmias
- antiemetic (centrally antidopaminergic)
- prevents histamine release
What are some cons to using a phenothiazine (such as ace) for sedation?
- Not reversible
- Hypotension (alpha blockade, vasodilation)
- Platelet aggregation inhibitor
- long acting, esp. with liver dz
- mild resp depressant
- no analgesia
- Minimal sedation in cats
What are some pros of using an alpha 2 agonist (such as dexmed or xylazine) for sedation?
- Excellent sedation
- Excellent muscle relaxant
- Mild analgesia
- Reversible with atipamezole or yohimbine
What are some cons to using an alpha 2 agonist (such as dexmed or xylazine) for sedation?
- Hypertension (alpha 1/2 stim, vasoconstriction), followed by hypotension (central symp blockade resulting in decr in CO)
- Severe bradycardia (reflex bradycardia and central symp blockade)
- May cause emesis
- 1st/2nd/3rd degree AV block
- Depresses resp center
- Promotes diuresis
- Inhibitis insulin, may produce hyperglycemia
What are some pros to using a benzo for sedation?
- Minimal CV effects
- Amnestic
- Midaz = water soluble, can be given IM/SQ
- MAC sparing
- Reversible w/ Flumazenil
- Anticonvulsant
- Good muscle relaxant
What are some cons of using a benzo for sedation?
- May cause excitement in cats/some dogs
- Prolonged effects w/ liver insufficiency
- Diazepam not water soluble - ONLY IV
- No analgesia
- Controlled substances
Combining what two types of agents creates neuroleptanalgesia?
Opioids and a tranquilizer or sedative (typically a benzo)
What are the pros to using a full mu agonist as an emergency sedative?
- Excellent analgesia
- Reversible w/ naloxone, naltrexone
- Mild cardiopulm effects (bradycardia, decr RR, dose dependent)
- Synergistic w/ tranqs/sedatives
What are the cons of using a full mu agonist as an emergency sedative?
- Dysphoria/excessive sedation
- panting/hyperthermia in cats
- decr GI motility
- Controlled drugs
- Vomiting
- Excitement/aggression in some cats
- Resp depression
What are the pros to using a partial mu agonist as an emergency sedative?
- Less dysphoria than full mus
- Less resp/GI effects than full mus
- Butorphanol can be used as partial reversal agent
- Buprenorphine is long lasting and can be given transmucosally in cats
- Good analgesic effect w/o significant dysphoria in cats
What are the cons of using a partial mu agonist as an emergency sedative?
- Less analgesia provided than with full mu
- butorphanol is short acting
- controlled drugs
T or F: Etomidate is a great choice as an induction agent in all emergency patients
False; etomidate is actually contraindicated in many emergency patients because it can suppress adrenal function for up to 6 hours following a single dose and the stress response is often necessary for survival in emergent patients
What induction agent can cause direct myocardial depression in patients with catecholamine depletion?
Ketamine
What are the cons of using an opioid and a benzo as induction agents (neuroleptanalgesia)?
- Swallowing reflex maintained
- Noise-sensitive during induction
- Use of controlled drug
- Only effective in dogs and cats w/ severe CB or neuro depression
- Resp depression
When using the Doppler method to measure blood pressure, what does the value most closely represent in dogs vs. cats?
- Dogs - systolic arterial pressure
- Cats - MAP
A sudden decline in end-tidal CO2 in the face of normal ventilation could indicate what?
A drop in CO, a loss of perfusion to the lungs (PTE), or cardiac arrest
What types of patients should you strongly consider administering blood products to prior to anesthesia?
- Patients with acute blood loss
- Patients showing clinical signs of decr O2 delivery (tachycardia, tachypnea, lethargy, weakness)
- Elevated plasma lactate levels
- PCV <20%
If administering whole blood, approximately 2 ml/kg of whole blood can be expected to raise the PCV by what percentage?
1%