emergency Flashcards
what is anaphylaxis?
IgE mediated mast cell and basophil type 1 hypersensitivity reaction
adrenaline in anaphylaxis
0.5mg IM (0.5ml 1:1000)
other than adrenaline what other medication is given in anaphylaxis
chlorphenamine 10mg IV
hydrocortisone 200mg IV
what can be measured to identify anaphylaxis
serum tryptase
how long should anaphylaxis be monitored for?
up to 12 hours to look for biphasic reaction
how soon can you repeat adrenaline if no effect in anaphylaxis?
5 mins
causes of shock
obstructive- reduced cardiac flow (PE/ tension)/ reduced cardiac filling (tamponade)
distributive- sepsis, anaphylaxis, neurogenic
cardiogenic- MI, dysrhythmia
hypovolaemic- burns, haemorrhage, pancreatitis
what is a SOFA score
sequential organ failure assessment score
What is qSOFA score
quick SOFA
2+ refer to CCU outreach
used to diagnose sepsis
What is SIRS
systemic inflammatory response syndrome 2+ of: temp <36/ >38 HR >90 RR >20 WCC <4/>12 sepsis= SIRS + infection
what is septic shock
Sepsis + req vasopressive medication to maintain MAP >65 + serum lactate >2
stage I (compensated) blood loss
<1000ml loss HR <100 BP normal RR normal UO >30ml/ hour
stage II (Mild) Blood loss
1000-1500ml HR>100 CRT>2 posts hypotension 20-30ml/hr UO Anxious/ agitated
stage III (moderate) blood loss
1500-2000ml HR>120 SBP<90 CRT >3 UO <20ml/hr
Stage IV (severe) blood loss
>2000ml HR>140 SBP<80 anuria Reduced AVPU
hypovolaemic shock
preload decreased
CO increased
afterload increased
tx IV fluids
cardiogenic shock
preload increased
CO decreased
afterload increased
tx Inotropes and revascularisation
distributive shock
preload decreased
CO increased
afterload decreased
tx pressors, IV fluids
what is acute respiratory failure?
PaO2 <8
Type 1 normal PaCO2 due to ventilation:perfusion mismatch
Type 2 raised PaCO2 due to alveolar hypoventilation
flow rate through nasal cannula
2L (30%)
flow rate through face mask
6L (60%) can be combined with NC
Shockable pulse (VF/ pulseless VT)
shock immediately
after 3rd shock amiodarone 300mg IV and adrenaline 10ml of 1:10000 (1mg)
non-shockable (PEA/ Asystole)
adrenaline 10ml 1:10000 Asap then after every 3-5 minutes
4Hs and 4Ts
Hypoxia hypovolaemia hyperkalaemia hypothermia thrombosis tension tamonade toxins
opiate OD
naloxone
TCA OD
activated charcoal, diazepam or fits,
may require sodium bicarb
cardiac monitoring