Nervous system develops from _______
ECTODERM
Outermost layer of embryo
Ectoderm
Skin (dermis), muscles, vascular systems
Mesoderm
GI and respiratory system
Endoderm
2 phases of nervous system development
- neural tube formation
- brain differentiation
When does neural tube formation happens?
Days 18-26
When does brain differentiation happens?
Day 28 onwards….
Longitudinal thickening of ectoderm
Neural Plate
Edges of the neural plate folds
Neural Groove
The separation of cells adjacent to the groove from the ectoderm
Neural Crest
4th step of neural tube formation
Closure of neural tube
When does the superior neuropore closes?
Closure by day 27
When does inferior neuropore closes?
Closure AFTER 3 days
What does superior neuropore corresponds to?
Brain
What does inferior neuropore corresponds to?
Spinal Cord
Concentric layer comprising of cell bodies (gray matter)
Mantle layer
Concentric layer comprising of axons (white matter)
Marginal layer
For motor function
Anterior basal plate
For sensory function
Posterior alar plate
What are the 3 primary enlargement in brain differentiation?
- Prosencephalon
- Mesencephalon
- Rhombencephalon
Secondary enlargement of prosencephalon
Telencephalon and Diencephalon
Secondary enlargement of mesencephalon
Mesencephalon
Secondary enlargement of rhombencephalon
Metencephalon and Myelencephalon
Mature structures of Telencephalon
- Cerebral Hemispheres
- Lateral Ventricle
