Embryology - Videos Flashcards
Corona radiata
Dense layer of cells surrounding the oocyte
Zona pellucida
Glycoprotein protective coat surrounding oocyte, acts in sperm binding, fertilization, block to polyspermy and premature implantation
ZP3
Receptor protein in zona pellucida, binds to sperm
Sperm binding
Reaction where sperm binds to ZP3 receptors on zona pellucida
Acrosomal reaction
Activated when sperm binds to zona pellucida, acrosomal enzymes released and digest zona pellucida proteins
Perivitalline space
Space between oocyte and zona pellucida
Fast block to polyspermy
Oocyte cell membrane depolarization in reaction to sperm fusion, stops other sperm from fusing
Slow block to polyspermy
Sperm fusion activates calcium wave that triggers cortical granule secretion and destruction of ZP3 blocking sperm binding
Cortical granule
Specialized granule just beneath the plasma membrane of oocyte that contains enzymes that destroy ZP3
Pronucleus
Term describing the maternal and paternal nuclei before fusion in the oocyte
Zygote
Diploid cell formed when maternal and paternal pronuclei fuse
Cleavage
Rapid mitotic division after fertilization, first on happens at 30 hours
Blastomere
Diploid cells formed by early zygotic divisions through cleavage
Morula
Cluster of 16-32 identical blastomeres, enters the uterus cavity around day 4
Blastocoele
Cavity formed when uterine milk penetrates the blastomere and form a cavity during day 5
Blastocyst
Early developmental stage of embryo following morula, consists of trophoblast, embryoblast and blastocoele, forms around day 5 and hatches from zona pellucida
Implantation
Happens 6-7 days after fertilization, can happen only if the endometrium wall is properly prepared
Decidua
Name for the endometrium during pregancy