Embryology II Flashcards
Early CV system: development of primitive heart:
Before 3rd week first blood cells arise in yolk sac and spaces in mesoderm > gaps in endothelial cells along with mesoderm spaces
By 3 weeks there is a system of paired blood vessels > swellings of these vessels merge together to form primitive heart
Early CV system: how does embryo initially receive O2?
Diffusion from nearby maternal blood
First heart beat?
21-22 days
Development of the heart: first blood flow
Occurs inferiorly to superiorly
Development of the heart: heart tubes bend creating three areas:
Bulbous cordis (superior)
Ventricle
Atrium (inferior)
Development of the heart: continued folding results in:
Atrium moved superiorly towards BC dividing in to two parts
Ventricle moves inferiorly deciding in to two parts
BC becomes truncheon arteriosis then aorta
Development of the heart: what are the ‘cushions’
Thickening so between atria and ventricles that separate them allowing unidirectional bood flow. Eventually become the valves
Development of the heart: Umbilical vein
Return from placenta and empty in to inferior vena cava via ductus venosis
Development of the heart: Umbilical artery
Extends from internal iliac artery through the umbilical cord to placenta
Development of the heart: Ductus venosis
S a vascular shunt from umbilical vein to inferior vena cava
Development of the heart: foraman ovale
Hole in the atrial septum allowing blood flow directly between atria
Development of the heart: ductus arteriosis
Vascular shunt from pulmonary trunk to aorta bypassing pulmonary circulation
Respiratory development WEEK 4
- Laryngotrachial diverticum arises from foregut
- lung bud arises from laryngotrachial tube
- bronchial buds lengthen and become primary bronchi
- RHS = 3 secondary bronchi
- LHS = 2 secondary bronchi
Repiratory system WEEK 5
- Secondary bronchial buds continue to generate successive branches
- surrounding mesoderm will become surrounding CT, cartilage, muscles, blood, lymphatic system
GI Tract development
- Wk 4 primordial gut (foregut, midgut, hindgut) forms from endoderm folding as it creates endoderm tube
- surrounding mesoderm will create muscles and CT tissue of GI tract