Conception And Placentation Flashcards
Factors of FEMALE fertility
Number of oocyte Age BMI AND BF% Environment Disease
What are the events that must take place for conception to occur
Ovulation and transport of oocyte >
coitus >
transportation and capacitation of spermatozoa >
completion of meiosis II of the oocyte
Factors of MALE fertility
Age (sperm quality and amount)
Sperm concentration
Sperm mobility
Outline events of early embryology
- Sperm capacitates and erodes through CORONA RADIATA and ZONA PELLUCIDA >
- oocyte completes meiosis and male and female pronuclei join to form zygote
- zygote undergoes CLEAVAGE until it creates a MORULA
- morula enters uterus and receives uterine secretions creating fluid Antrum and becomes BLASTOCYST
- blastocyst: INNER CELL MASS & TROPHOBLAST
-
Implantation process: trophoblast:
- Trophoblast differentiates in to: SYNSYTIOTROPHOBLAST & CYTOTROPHOBLAST
Implantation: syncytiotrophoblast
- syncytiotrophoblast: erodes endometrium and create lucanae which merge to form intervillous space to fill with maternal blood.
Implantation: CYTOTROPHOBLAST
- CYTOTROPHOBLAST: develops in to chorion and amnion. Extensions of the chorion (chorionic villi) develop bathed in maternal blood in IV space
Implantation: Decidua
- endometrium surrounding the blastocyst becomes the decidua:
DECIDUA BASALIS forms on maternal side of placenta and is what chorionic villi anchor to
DECIDUA CAPSULARIS covers the blastocyst as it enters the uterine cavity, will eventually degenerate
Placentation: syncityotrophoblasts
Erode spiral arteries allowing maternal blood to fill lucanae/intervillous space
Placentation: chorionic villi
Develop within intervillous space and anchor to decidua basalis
Foetal blood vessels develop within chorionic villi
Functions of placenta
Transportation
Immunological
Hormone synthesis
Metabolism
Factors necessary for the establishment of pregnancy (3)
Cells of zygote and blastocyst must be well nourished
Implantation must occur in endometrium of uterus
Corpus luteum must be maintained