Embryology II Flashcards

Neurulation, Folding, and Development of the Nervous System

1
Q

After the notochordal process approaches the prechordal
plate, the floor of the process “fuses” with the endoderm it is now called ___

A

notochordal plate

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2
Q

what is the opening that allows communication between the amniotic cavity and the umbilical vesicle

A

neurenteric canal

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3
Q

the neurenteric canal is formed where the ____ opened into the notochordal canal

A

primitive pit

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4
Q

the notochordal plate progress to the ____

A

notochord

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5
Q

which direction does the notochord transition go from

A

cranially –> caudally

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6
Q

when is there no longer a neurenteric canal

A

after full development of the notochord

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7
Q

notochordal plate cells proliferate and fold
inwards, forming the fully-developed ___

A

notochord

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8
Q

The notochord is no longer a ___ canal

A

hollow

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9
Q

what is between the notochord and the umbilical vesicle

A

embryonic endoderm

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10
Q

the ectoderm above the notochord develops into ___

A

neural plate

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11
Q

what is the stop signal for notochord development anteriorly

A

prechordal plate

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12
Q

what develops into the oropharyngeal membrane

A

prechordal plate

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13
Q

what is special about the oropharyngeal and cloacal membranes

A

they only have ecto and endoderm layers

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14
Q

what does the cloacal membrane become

A

anus

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15
Q

Small, vascularized diverticulum (outpouching) from the caudal wall of umbilical vesicle, extending into connecting stalk

A

allantois

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16
Q

what day is the allantois formed

A

day 18

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17
Q

Allantois functions in development of what

A

early blood formation
bladder development
uranchus

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18
Q

what does the uranchus become in adults

A

median umbilical ligament

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19
Q

Notochord induces overlying ectoderm to form
the neural plate is what process

A

neurulation

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20
Q

what is special about neuroectodermal cells

A

tall and columnar

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21
Q

what does the neuroectoderm give rise to

A

CNS
retina
other tissues from neural crest

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22
Q

on day __ the neural plate invaginates to form the neural groove – neural folds are found on either side of the groove

A

18

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23
Q

the neural tube is formed by ____ fusing together

A

neural folds

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24
Q

the neural tube is primordium of what

A

CNS

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25
when does neurulation end
when the tube is completely closed end of week 4
26
which direction do the neural crest cells migrate
dorso-laterally
27
what CN ganglia do neural crest cells help develop
CN V, VII, IX, X
28
what NS do the neural crest cells help develop
Autonomic nervous system ganglia
29
neural crest cell derivatives form the _____ and ____ matter
arachnoid and pia
30
melanocytes are derivatives of ___
neural crest cells
31
craniofacial bone and cartilage are derivatives of ____ cells
neural crest
32
Intraembryonic mesoderm proliferates to form a thick column of mesoderm on either side of the notochord beside the axis is called what
paraxial mesoderm
33
cuboidal masses of mesoderm on either side of the notochord, visible along the dorso-lateral surface of the embryo on each side of the neural tube
somite
34
somites give rise to:
axial skeleton, musculature and dermis of area
35
cardiogenic mesoderm gives rise to __
embryonic heart primordia
36
on day __ the embryonic heart primorda is formed
20
37
primordium of _____ appears as isolated spaces in the lateral mesoderm and cardiogenic mesoderm
intraembryonic coelom
38
what shape is the intraembryonic coelom formed into
single horseshoe
39
what are the 2 layers that the intraembryonic coelom divides the lateral mesoderm into
1. somatic /parietal layer 2. splanchnic / visceral layer
40
what layer of lateral mesoderm covers the amnion
somatic or parietal layer
41
what layer of the lateral mesoderm covers the umbilical vesicle
splanchnic or visceral layer
42
on day ___ the coelomic spaces are a continuous cavity
21
43
the somatic mesoderm and the overlying ectoderm later forms the body wall
somatopleure
44
the splanchnic mesoderm and the underlying intraembryonic endoderm later forms the embryonic gut
splanchnopleure
45
what is between the somatopleure and splanchnopleure
intraembryonic coelom
46
intraembryonic coelom develops into 3 main body cavities which are
1. pericardial cavity 2. pleural cavity 3. peritoneal cavity
47
The bilaminar embryonic disc is converted into a trilaminar embryonic disc during
gastrulation
48
the ___ results from migration of epiblastic cells to the median plane of the disc
primitive streak
49
Invagination of epiblastic cells from the primitive streak gives rise to mesenchymal cells that migrate ventrally, laterally, and cranially between the
epiblast and hypoblast
50
As soon as the primitive streak begins to produce mesenchymal cells, the epiblast is known as
embryonic ectoderm
51
Some cells of the epiblast displace the hypoblast and form
embryonic endoderm
52
the anterior and posterior ends of the embryo move ventrally. Also known as cranial-caudal folding
median plane
53
the lateral edges of the embryonic disk move ventrally. Also known as lateral folding * The edges “roll” ventrally towards the umbilical vesicle
horizontal folding
54
when does embryonic folding occur
start in end of 3rd week see at 4th week
55
As it folds ___, the brain vesicles first begin to appear, and a few somites are obvious
cranially
56
As it folds ___, the body wall is formed
laterally
57
Part of the endoderm of the umbilical vesicle is incorporated into the embryo as the
foregut
58
what is the foregut between
brain and heart
59
the primordium of the mouth
stomedeum
60
what separates the foregut form the stomodeum
oropharyngeal membrane
61
develops into the central tendon of the diaphragm and separates the abdominal cavity from the thoracic cavity
spetum transversum
62
the location of the heart changes based on what
head fold
63
what is primordium of the umbilical cord
connecting stalk
64
after lateral folding, the connection between the midgut and umbilical vesicle is reduced to an ___ duct
omphaloenteric duct
65
connective tissue; cartilage; bone * striated and smooth muscles; heart, blood, and lymphatic vessels; kidneys; * ovaries; testes; genital ducts; serous membranes lining the body cavities (pericardial, pleural, and peritoneal); spleen; and cortex of suprarenal glands
mesoderm derivatives
66
epithelial lining of the digestive and respiratory tracts, parenchyma of the tonsils * thyroid and parathyroid glands, thymus * liver, and pancreas, epithelial lining of the urinary bladder and most of the urethra * epithelial lining of the tympanic cavity, tympanic antrum, and eustachian tube
endoderm derivatives
67
CNS, PNS; sensory epithelia of the eyes, ears, and nose * epidermis and its appendages (hair and nails); mammary glands; subcutaneous glands; enamel of teeth; pituitary gland * Neural crest cells – discussed previously
ectoderm derivatives
68
on day __ the neural plate can be seen
19
69
on day __ neurulation is complete with closure of neuropores
27
70
on day __ the cranial 2/3 of the neural tube makes the brain and the caudal 1/3 makes the spinal cord
22
71
The neural folds fuse at the level of the ___ somite, proceeds cranially and caudally
5th
72