Embryology: Folding and Body Cavities Flashcards
in the folding of the embryo, what three fold that happen at the sam time?
head, tail and transverse
Before any folding occurs, what structure is most rostral?
septum transversum –> gives rise to Diaphragm
Around what week does folding occur?
4th week
As the neural tube moves forward, what begins to close?
rostral neuropore
The notochord gets tucked ventrally and caudally, what now is the most rostral structure? most caudal?
from rostral - caudal:
intra-embryonic coelum –> heart tubes –> septum transversum
Before folding, what three things sit in the prochordal mesoderm?
1) Septum transversum
2) Heart tube
3) Intra-embryonic coelum
the membrane connecting the notochord with the prochordal mesoderm is?
oropharyngeal membrane
What is the purpose of the oropharyngeal membrane?
acts as a “hinge” or pivot point and all structures will rotate around each other
During this process a portion of yolk sac becomes engulfed as well and forms the?
foregut
the remainder of the yolk sac that is not engulfed during folding goes?
it is squeezed out the ventral midline
as the neural tube folds caudally, what moves?
the collecting stalk and alianois get shifted ventrally
after the head fold, where is the oropharyngeal membrane located?
ventral to all structures ( heart tubes, IEC and septum transversum)
what makes up the amniotic membrane?
EEM+Ectoderm
What are the clinical significances of the head fold?
1) foregut formed
2) oropharyngeal membrane ventral toCNS
3) heart is ventral to CNS and gut
4) heart is dorsal to intraembryonic coelom
5) septum transversum is caudal to heart
6) rostral neuropore closes
7) ectoderm now covers rostral end of embryo while amniotic cavity surrounds the rostral end of embryo
What are rostral neural tube defects?
anencephaly and exencephaly
during the tail fold, the portion of the yolk sac that gets engulfed forms the?
hind gut
the membrane connecting the notochord/neural tube with EEM is?
cloacal membrane
the cloacal membrane will give rise to?
the anus