Embryology Final Flashcards
Three stages of heart formation
- Formation of primitive heart tube
- Cardiac looping
- Cardiac septation
What are the three Layers of the heart tube
Endocardium, myocardium, epicardium
Condition where both aorta and pulmonary artery arise from the right ventricle
Double Outlet Right Ventricle (DORV)
Pulmonary valve not formed properly
Pulmonary atresia
Improper blood flow in the pulmonary artery
Pulmonary stenosis
Types of Septum Formation
-Endocardial cushions (Two masses)
-Single tissue mass
Cardiac septation process
- Endocardial cushion
- artioventricular septum
- Interventricular septum
- Septum primum/foramen primum
- Foramen secundum
- Septum secundum/foramen ovale
- Spiral septum
Clinical correlates of cardiac septation
- Excessive resorption of septum primum
- Absence of septum secundum
- Absence of septum primum and septum secundum
Differences in circulation in fetal heart
-oxygenated blood comes through IVC from the placenta
-blood for pulmonary artery will go to the aorta through ductus arteriosus
-Blood shunts from R to L atrium through foramen ovale
How long does ductus arteriosus stay open
First 3 months after birth
Blood vessel development occurs by:
Vasculogenesis and Angiogenesis
Vessels arise from angioblasts
Vasculogenesis
Vessels sprout from existing vessels
Angiogenesis
Growth factor important in Vascular development
Vascular endothelial growth factor (VEGF)
What does the intermediate mesoderm divide into
Segmented and unsegmented intermediate mesoderm
3 stages of kidneys
- Pronephros (beginning/regresses)
- Mesoephros (also regresses)
- Metanephros (forms permanent kidney)
Where does pronephros start
Segmented intermediate mesoderm
Where are mesonephros formed
Unsegmented intermediate mesoderm
Mesonephric excretory vesicles are connected to
Wolffian Duct
What is the function of mesonephros
Acts as a collection duct/removal of waste products and fluid
What combines in mesanephros to create the renal corpuscle
Bowman’s capsule and glomerulus
What does a nephron consist of
Renal corpuscle, proximal convoluted tubule, loop of Henle and distal convoluted tubule
Composition of uriniferous tubules
RC, PCT, LOH, DCT + collecting duct and collecting tubule
Where do the collecting tubule and collecting duct come from
Uteretic bud
Most glial cells differentiate from _______
Neuroepithelial Cells