Embryology Flashcards
1
Q
What genes are supper important in the gastrulation and eventually the formation of ribs?
A
The HOX genes
2
Q
What will the notochord eventually form?
A
The nucleus pulposus of the intervertebral discs
3
Q
What are the 3 important things that interact to form the limbs?
A
- Apical ectodermal ridge AER
- Zone of polaring activity
- Progress zone
4
Q
What are the factors that influence the limb formation?
A
- Hox genes (13 = hand, 12 = carpe, 11 = forename, 10= humerus and 9 = scapula)
- Sonic Hedgehog
- Pax-3
- c-Met
- FGF
- Retinoic acid
5
Q
Congenital Clubfoot (talipus equinovarus) is the result of a problem in which step of limb formation?
A
The rotation of the limb buds accompanied by redistribution of myotome and dermatome
6
Q
What gene is responsable for Achondroplasia?
A
FGFR3
