Embryology Flashcards
PA 1 - neural crest cells
midbrain rhombomeres 1 and 2
PA 2 - neural crest cells
rhombomere 4
PA 3 - neural crest cells
rhombomere 6
PA 4 - neural crest cells
rhombomere 8
PA 1 - nerve
V trigeminal Branches: - Ophthalmic - Mx - Md
PA 1 - muscles
Mastication - temporal, masseter, medial/lateral pterygoids Mylohyoid Anterior digastric Tensor tympani Tensor veli palatini
PA 1 - skeleton
Meckel’s cartilage Malleus Incus
PA 2 - nerve
VII facial - chorda tympani - taste
PA 2 - muscles
Facial Expression - buccinator, auricularis, frontalis, platysma, orbicularis oculi, orbicularis ori Posterior digastric Stylohyoid Stapedius
PA 2 - skeleton
Reichert’s cartilage - stapes - styloid - lesser hyoid
PA 3 - Nerve
IX glossopharyngeal - sensation: pharynx, mid ear, root of tongue - Taste root of tongue
PA 3 - muscles
stylopharyngeus
PA 3 - skeleton
greater hyoid
PA 4-6 - nerve
X vagus - parasympathetic innervation
PA 4-6 - muscles
Cricothyroid Levator veli palatini Contrictors of pharynx Larynx muscles
PA 4-6 - skeleton
laryngeal cartilages
pharyngeal pouches are where?
between arches, interior
pharyngeal grooves/clefts are where?
between arches, exterior
Fate of 1st pouch
external auditory meatus/tympanic cavity eustachian tube
Fate of 2nd pouch
obliterated by tonsil
fate of 3rd pouch
inferior parathyroid thymus
fate of 4-5 pouches
superior parathyroid ultimobranchial body (C cells thyroid)
Fate of 1st groove/cleft
external auditory meatus/tympanic cavity eustachian tube
Fate of clefts/grooves 2-6
dissapear
What do the neural crest cells differentiate into (general)?
Nerves Bones and CT of head Cells Endocrine Eyes Heart
What nerve tissue is derived from neural crest cells?
ganglia of CNS Craniospinal sensory and parasympathetic ganglia GI nerves Glial cells - Schwann cells Carotid body
What bones and CT of the head are derived from neural crest cells?
meninges skull mx md larynx hyoid auditory ossicles Teeth - dentin, cementum, pulp, PDL PHARYNGEAL ARCHES
Which specific cell types are derived from neural crest cells?
melanocytes C (calcitonin) cells of thyroid adipocytes
Which parts of the endocrine system are derived from neural crest cells?
C (calcitonin) cells of thyroid Adrenal medulla
Which parts of the eye are derived from neural crest cells?
pigmented retina cells smooth muscle cornea
Which parts of the heart are derived from neural crest cells?
carotid body Middle portion cardiac outflow tract
Which germ cell layers form the pharyngeal arches?
Lateral plate mesoderm paraxial mesoderm neural crest cells
Fates of neuroectoderm
posterior pituitary pineal body retina CNS
Fates of intermediate plate mesoderm
urogenital system
Fates of lateral plate mesoderm
Heart Hematopoetic system lymphoid system Connective tissue spleen adrenal cortex pharyngeal arches Serous membranes (pleura, pericardium, peritoneum)
Fates of paraxial mesoderm
muscles of entire body Bones of most of body (except head) dermis pharyngeal arches connective tissue
Fates of ectoderm
Epidermis hair nails mammary glands anterior pituitary lens of eye inner ear tooth enamel
Fates of endoderm
GI lining lungs liver pancreas gallbladder bladder thyroid follicular cells tympanic cavity tonsils parathyroid
What happens during the embryonic period phase 1? timeline?
weeks 0-3 - cellular proliferation and migration Wk 1: morula to blastocyst Wk 2: formation of bilaminar disk Day 14-16: Gastrulation - form trilaminar disk
What happens during embryonic period phase 2? timeline?
Weeks 4-8 - differentiation Formation of neural tube Differentiation of mesoderm Folding PA formation Development of head, face, OC
What happens during embryonic phase 3? timeline?
Growth and maturation Weeks 8-40 (delivery)
role of PA 1 in tongue development
lingual swellings - mucosa of body N: V trigeminal
Role of PA 2 in tongue development
copula - overgrown
Role of PA3 in tongue development
Large ventral part of hypopharyngeal eminence - mucosa of most of root N: IX glossopharyngeal
Role of PA4 in tongue development
Small dorsal part of hypopharyngeal eminence - mucosa of tiny part of root N: X vagus
Role of somites in tongue development
myoblasts - muscles of tongue N: XII hypoglossal