Embryology Flashcards

1
Q

give a brief time line of embryological events

A

Weeks 1 & 2

Week 3 – gastrulation, neurulation, somite formation

Weeks 4 – 8 organogenetic period

Week 9 onwards – maturation of organ systems

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2
Q

for how long does reproductive system organogenesis extend

A

beyond 8 weeks - even extends beyond post natal period

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3
Q

how are the urinary and report systems linked embryologically linked

A

urinary system for the template for the reproductive system

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4
Q

urinary development recap - three sets of kidneys

A

Pronephros – cervical region – vestigial

Mesonephros – thoracolumbar region – briefly functional

Metanephros – pelvic region – functional

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5
Q

urinary development recap -

what does the cloaca divide to form

A

rectum (GI tract) and anteriorly the urogenital sinus

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6
Q

urinary development recap - what drains into the urogenital sinus

A

the mesonephric duct

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7
Q

urinary development recap - what does the urogenital sinus later go on to form

A

the urinary bladder, its caudal end forms the urethra

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8
Q

what happens in weeks 5-6 of repro organ development

A

genital (gonadal) ridge formation

  • mesonephros froms a long ovoid structure with the thoracic and upper lumbar vertebrae
  • medial part of mesonephric ridge becomes thickened to for a genital/gonadal ridge
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9
Q

what happens once the genital ridge has formed

A

germ cells migrate from the yolk scan, via dorsal mesentery, and embed into the primitive sex cords (formed from the mesenchyme of the genital ridges

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10
Q

what is the genital ridge + germ cells known as

A

the indifferent gonad (hasn’t differentiated yet into male/female)

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11
Q

what happens if the germ cells don’t migrate

A

no gonads form

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12
Q

how is the paramesonephric duct formed

A

epithelium of the mesonephros invaginates to form a tube - develops lateral to developing gonads and mesonephric duct

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13
Q

what does the indifferent gonad form eventually

A

ovary

testis

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14
Q

what does the mesonephrc duct (wolfing duct) form eventually

A

epididymis, vas deferens, seminal vesicle

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15
Q

what does the paramesnephric duct (mullein duct) form eventually

A

fallopian tube, uterus, cervix, vagina

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16
Q

male summary:

A

gonad forms testis

mesonephric duct develops into epididymis, max deferent, seminal vesicle

paramesonephric duct degenerates

urogenital sinus forms bladder, urethra, prostate

17
Q

female summary

A

gonad forms ovaries

mesonephric duct degenerates

paramesonephric duct forms fallopian tube, uterus, cervix, upper part of vagina

urogenital sinus forms bladder and lower part of the vagina