embryology Flashcards
memorize
limb buds appear in
4th week
limb buds derived from
mesoderm,ectoderm and parietal layer of lateral mesoderm
ectoderm proliferates into
Apical Ectodermal Ridge (AER)
what does AER do
stimulates the mesenchyme to be a population of undifferentiated rapidly proliferting cells called the prgress zone.
development of the limb proceeds in what direction
proximodistally
6th week
hand and foot plates formed
fingers and toes are formed how?
by cell death of the ridge into 5 parts
development of upper limb is faster than lower limb by
1 to 2 days
7th week
limbs rotate in different directions
upper limb rotates
90° laterally. extensor muscles lie laterally and posterioly and thumbs lie on the lateral side.
lower limb rotates
90° medially extensor muscles lie medially and big toe is medial.
6th week again
first hyaline cartilage models form
12th week
primary ossification centers are present in all long bones .