Embryology Flashcards

1
Q

What part of the primitive embryo does the respiratory system develop from?

A

Ventral all of the foregut

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2
Q

What is the laryngeotracheal groove?

A

Early lung buds

Forms from foregut in 4th week before budding out

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3
Q

What happens by week 8 of development re respiratory system?

A

Lung buds almost completely branched out

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4
Q

How does the trachea develop in the embryo?

A

Branches out of the oesophagus

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5
Q

What is the laryngeotracheal groove covered in?

A

Mesoderm

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6
Q

What does the visceral pleurae develop from?

A

Splanchnic mesoderm

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7
Q

What does the parietal pleura develop from?

A

Somatic mesoderm

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8
Q

How do the pleura form around the lungs?

A

The lungs bud out and invade the pleural cavity

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9
Q

At what stage of gestation do the primitive lungs appear?

A

26 days

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10
Q

What happens during the pseudo glandular stage of development?

A

Setup of all pulmonary structures except those required for gas exchange

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11
Q

What happens in the canalicular stage of development?

A

Terminal bronchioles give rise to tubes that make up respiratory part of the lung
Differentiation of epithelium into different types of pneumocytes

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12
Q

What happens during the saccular stage od development?

A

Formation of alveolar sacs separated by primary septa

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13
Q

What happens in the alveolar stage of development?

A

Alveoli increase in number and then in size

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14
Q

What are 4 congenital respiratory conditions?

A

Respiratory distress syndrome- Surfactant deficiency
Accessory lobe- too much proliferation
Agenesis- lung hasn’t developed
Azygous vein invaginated into lung and lung grows around it

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15
Q

How many parts does the diaphragm develop from?

A

4

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16
Q

What are the 4 parts the diaphragm develops in?

A

Septum transversum= central tendon
Pleuroperitoneal membrane= primitive diaphragm
Dorsal mesentery of oesophagus= medial portion and crura
Muscular ingrowth of lateral body walls= peripheral parts

17
Q

How does the septum transverse develop?

A

Initially opposite C3-5

Descends and brings innervation from C3-5 with it

18
Q

What are congenital abnormalities involving the diaphragm?

A

Failure od diaphragm to fully close during development
Herniation of abode contents into chest
Pulmonary hypoplasia