Embryology Flashcards
produces blastomeres
Mitotic divisions
Week 1
16 cell structure at 3 days post fertilization
Morula
Cells that implant into uterine wall at day 6
Trophoblast
Form embryo of fetus and embryo blast
Inner mast cells
Trophoblast into 2 layers
Cytotrophoblasts
Synctiotrophoblasts
Produces hcg
In contact with maternal blood supply via trophoblastic lacunae
Synctiotrophoblast
Inner cell layer form new trophoblastic cells
Lines primitive yolk sac
Cytotrophoblast
Embryoblast (inner cell mast) forms 2 layers that form flat disc
Epiblast
Hypoblast
Source of all germ layers
Embryonic ectodermal tissue
Small cavity = amniotic cavity
Epiblastic cells = amino lasts
Epiblast layer
Cuboidal epithelium
Forms primitive yolk sac
Becomes endodermis tissue of yolk sac
Hypoblast
Extraembryonic mesoderm divides into
Somatic
Splanchinic
Connecting stalk is future
Umbilical cord
Cytotrophoblast cells penetrate synctiotrophoblast forms
Primary villi
Extraembryonic splanchnic mesoderm covers
Yolk sac
Secondary and tertiary villi form barrier between
Maternal and fetal blood by the two layers of trophoblasts
Week 3 beginning of
Morphogenesis
Notochord formed
3 layer disc from bilaminar disc composed of ecto- endo- meso-derm
Formation of primitive streak
Week 3 Gastrulation
Epiblast cells through primitive pit form
Notochordal process
Epiblast cells lateral primitive streak form
Mesoderm
Epiblast cells staying form
Ectoderm
Epiblast cells on primitive streak
Endoderm
Germ layers derived from
Eps lasting cell layer of bilaminar disc
Epithelial lining of respiratory system and gi tract
Endoderm
Smooth and striated m Skeleton Reproductive Vessels ❤️
Mesoderm
Epidermis
Surface ectoderm
Nervous system
Neural crest
Neuroectoderm
Notochord process forms
Notochordal plate
Structure around which vertebral column forms
Inducer of neural plate formation
Notochord
Living derivative of notochord is
Nucleus pulposus
Paraxial mesoderm + notochord =
Neural tube induction
Neural crest and tube from
Ectoderm
Induction of notochord to form
Neural plate
Rectangular shaped pairs of paraxial mesoderm that form on either side of notochord
Somites
Axial skeleton at that level and dermis connected to it
Somite
Body cavities develop from
Lateral plate of intraembryonic mesoderm
Somatic mesoderm =
Parietal
Splanchnic =
Visceral
All systems and organs develop frontera layers
Most structural defects induced
Week 3-8 Embryonic period
Zygote
Sex determined
Initiation of cell division (cleavage)
23 to 46 chromosomes
Fertilization
Formation of neural tube in 3rd week when notochord and paraxial mesoderm induced neuroectoderm to form neural plate
Neurulation
Formation of neural tube starts with
Neural fold
Followed by neural tube and crest
Finally neuropores close
Neural tube wall formed by three layers
Ependymal
Mantle
Marginal
Ependymal gives rise to
All cell types of CNS
Mantle thickens to form
Alar plate (dorsal horn) Basal plate (ventral horn)
Axons from the mantle layer form
Marginal layer
Neural crest =
Dorsal root ganglia
Autonomic ganglia
Mesenchyme =
Meninges
Motor control of smooth ❤️ and glands require how many neurons and what are they called
2
Pre and post-ganglion neuron
How many motor neurons needed for skeletal muscle
1
Telencephalon
Cerebral hemispheres
Diencephalon
Thalamus and hypothalamus
Mesencephalon
Midbrain
Metencephalon
Pons and cerebellum
Myelencephalon
Medulla
In basal and alar plates, Gray matter organized in clusters of cell bodies called
Nuclei
3 flexures
Midbrain
Cervical (between hindbrain and cord)
Pontine (between metencephalon and myelecephalon)
Remnant of lumen of neural tube consisting of lateral ventricles, third and fourth ventricle, cerebral aqueduct and continuous with central canal of cord and subarachnoid space outside CNS
Ventricular system
Choroid plexus within ventricular system produces
Cerebrospinal fluid
Axial skeleton derived from
Somites
Somites differentiate into 2 aspects
Ventromedial
Dorsolateral
Ventromedial =
Sclerotome = vertebral body neural arch ribs
Dorsolateral =
Dermomyotome
Skin and mm
Notochordal process becomes notochord
Vertebral body forms around notochord
Nucleus pulposus left as living derivative of notochord
Notochordal stage
Paired sclerotome
Mesenchymal masses surround notochord and neural tube
Precartilaginous/mesenchymal stage
Each sclerotome differentiates into cranial loose and caudal dense cells
Resegmentation
Cranial loose and caudal dense cells separated by
IVD
Caudal part fuses with
Cranial part of subjacent sclerotome
By end of month 6 notochord cells replaced by what forming nucleus pulposus
Mesenchymal tissues
Mesenchymal cells differentiates into chondroblasts at chondrofication centers
Cartilaginous stage
How many primary and secondary ossification centers in each vertebrae
3
5
Deep back muscles innervated by dorsal rami
Epaxial
Thoracic abdominal body wall and limbs innervated by ventral rami
Hypoxial