Connective Tissue Flashcards
Mast cells contain what 2 mediators?
Histamine and heparin
What forms a continuum with epithelium, nervous and muscle tissues to maintain functionally integrated body?
Connective tissue
What are the functions of connective tissue
Structural support
Exchange
Defense
Fat storage
Consistency of connective tissue?
Liquid
Solid
Gas
Characteristics of connective tissue
Extracellular matrix
Ground substance
Fibers
Cellular components - fixed or transient in blood stream
Main cell type in connective tissue
Fibroblasts
What type of cell engulfs bacteria and debris by phagocytosis?
Macrophages
What type of cell presents antigens to lymphocytes
Macrophages
What type of cell stores and synthesizes triglycerides
Adipose cells
What type of cells are multi potential and a source for new cells
Mesenchymal cells
Fibers + ground substance =
Extracellular matrix
What type of transient cell synthesizes and secretes antibodies
Plasma cells
Two types of lymphocytes
B and T
Three types of connective tissue fibers
Collagen
Reticular
Elastic
Large unbranched connective tissue fiber formed by collagen protein
Collagen fiber
Small unbranched connective tissue fiber formed by collagen
Reticular
Medium branched connective tissue fiber formed by elastin
Elastic
What type of fiber provides resistance to tensile forces
Collagen
What protein is most abundant in connective tissue
Collagen
What’s a bundle of collagen fibrils
Fiber
What form is tropocollagen
Triple helix
3 polypeptide chains
Name collagen type
Fibrils form fibrils = bundles
Resist tension and are most abundant
Type I
Name collagen type
Fibrils only
Resist compression (cartilage)
Type II
Name collagen type
Fibrils from fibers
Reticular fibers
Maintain structure
Type III
Name collagen type
Tropocollagen molecule
Delicate structural support
Found in basal lamina
Type IV
What type of fiber
Framework but allows flexibility
Type III collagen fibers
Reticular fibers
What type of fibers Composed of chains of elastin protein Stretch Aorta, medium arteries Microfibrils first then elastin deposited
Elastic
What fills space between cells and fibers of connective tissue
Ground substance
What permits diffusion of oxygen and nutrients between cells and microvasulature of tissue
Ground substance
What type of connective tissue is located beneath epithelial linings of body surfaces, internal organs, and outer wall of blood vessels
Loose (areolar)
What type,of connective tissue has abundant ground substance
Loose
What type of connective tissue resists stress in all directions
Dense irregular
What type of connective tissue is found in tendons and ligaments
Dense regular
What type of c.t. Offers resistance to traction forces in one direction
Dense regular
What type of connective tissue is found in lung, vocal cords, ligamentum flava, aorta
Elastic ct
What type of connective tissue stretches and returns to original shape
Elastic
What type of connective tissue are cells and fluids freely mobile
Reticular
What type of tissue found only in umbilical cord
Mucous
What type of tissue has cells that give rise to most cells of loose connective tissue
Mesenchymal
What type of connective tissue has peripheral nuclei and fills space between other tissues
Adipose
What are two types of adipose tissue
Unilocular and multilocular
What is the most common adipose tissue
Unilocular
What adipose tissue releases leptin
Unilocular
What type of adipose tissue produces heat
Multilocular
What type of membrane lines body cavity that does not open to outside
Serous
What type of membrane lines joints and cavities of all freely moveable joints
Synovial
Specialized cells of synovial membrane are
Synoviocytes
What type of membrane is not lined with epithelium and has no tight junctions or basal lamina
Synovial
What type of membrane lines body cavities that open to outside
Mucous
What type of membrane has loose connective tissue called lamina propria
Mucous
What type membrane forms barrier to microbes
Mucous
What cells mediate inflammatory response?
Mast cells
