Embryo Flashcards
embryonic sources for eye tissue
neuroectoderm
surface ectoderm
mesenchyme (NCC and mesoderm)
neuroectoderm structures of eye
smooth m of iris
epithelium of ciliary body
retina
optic N
surface ectoderm structures of eye
lens
epithelium of cornea
mesenchyme structures of eye
sclera stroma of cornea choroid (NCC!!!!) stroma of iris ciliary m stroma of ciliary body
what is the anterior chamber of the eye?
between cornea & iris
what is the posterior chamber of the eye?
between iris & lens
what is glaucoma?
buildup of aqueous humor (can’t drain into sclera venous sinus)…abnormal development of sclera venous sinus needed to drain aqueous humor
where do extra-ocular muscles come from?
prechordal mesenchyme (develop down & around eye)
what does the hyaloid artery become?
central retinal artery
when do the choroidal vessels develop?
week 15
what is the optic N derived from/
neuroectoderm (extension of brain)
what is the optic stalk?
neuroectoderm..extension of the brain..NOT the optic N (a placeholder where optic N can grow its fibers)
what is the importance of the optic stalk?
provides pathway for neurons of ganglion cells to grow back to brain
How does papilladema occur?
retinal vessels (central retinal A & V) are covered by meninges & lie in extension of subarachnoid space so increased intracranial pressure can spread to eye (optic disc bulge)
what is the embryonic cause of coloboma?
failure of optic fissure to close leaving gap in eye structure (runny iris)
what are the main results of rubella virus for eye development?
cataracts, microphthalamos, glaucoma, pigmented retinopathy
what do all structures of membranous labyrinth?
surface ECTODERM
what does the bony labyrinth come from?
condensation of mesenchyme
what do the vacuoles of bony labyrinth become?
scala vestibuli, scala tympani, perilymphatic space (semicirc ducts)
causes of congenital deafness
maldevelopment of sound conduction apparatus of middle & external ears
neurosensory structures of inner ear
infection
sound conduction issues assoc w/
First Arch Syndrome
Abnormalities of malleus & incus
Congenital fixation of stapes
neurosensory structures of inner ear…
issues w/ surface ectoderm
what infections can cause congenital deafness?
rubella (weeks 7-8 can cause defects in spiral organ)
Cytomegalovirus (sensiorineural deafness)
Toxoplasmosis
Syphilis
Zika
what gives rise to the semicircular ducts?
utricular region of otic vesicle
