Embryo

Question 1

¨Neuroectodermal(neuroepithelial) cells of neural tube give rise to:

Answer 1

Question 2

Location of neuroblast formation, what type of cells is it made of?

Answer 2

ventricular zone (made of epyndymal cells)

Question 3

What area forms gray matter, what type of cells?

Answer 3

Intermediate zone, forms from neurioblasts that migrate from ventricular zone that become neurons and glial cells

Question 4

Divisions of intermediate zone

Answer 4

Question 5

What forms white matter and what does it contain

Answer 5

Marginal zone, contains nerve fibers (axons) of the neuroblastsof the intermediate layer and glial cells

Question 6

What form Dorsal Root Ganglia

Answer 6

Neural crest cells

Question 7

What seperarates alar and basal plates

Answer 7

sulcus limitans

Question 8

From where does the brain develop

Answer 8

¨neural tube cranialto the 4thpair of somites

Question 9

3 primary brain vesicles prior to closure of anterior neuropore

Answer 9

Question 10

What develops between rhombencephalon and spinal cord (4th week)

Answer 10

cervical flexure

Question 11

What develops between prosencephalon & rhombencephalon

Answer 11

¤Midbrain (mesencephalic, cephalic, cranial) flexure

Question 12

What allows for the formation of the 4th ventricle

Answer 12

Pontine flexure (rhombencephalon folds in on itself)

Question 13

Vesicles of prosencephalon of 5th and 6th weeks

Answer 13

Telencephalon and Diencephalon

Question 14

Vesicles of Rhombencephalon of 5th and 6th weeks

Answer 14

Metencephalon and myelencephelon

Question 15

When and from what does the cerebellum form

Answer 15

During 5th week, from rhombic lips. Lips fuse by 8th week, lobes and vermis by 12

Question 16

Three primary sequential events during cerebellar development

Answer 16

1. Patterning of MHB junction (isthmic organizer) and cerebellar angle
2. Development of 4thventricular roof
3. Development of cerebellar hemispheres & vermis

Question 17

Divisions of roof of 4th ventricle

Answer 17

Question 18

Primary events of forebrain development

Answer 18

1. Prosencephalic formation
2. Prosecephaliccleavage
3. Prosencephalic midline development

Question 19

What is formed by horizontal prosencephalon folding

Answer 19

paired optic vesicles, olfactory bulbs & tracts

Question 20

What is formed by transverse prosencephalon folding

Answer 20

Seperates diencephalon and telencephalon, Diencephalonforms portion of basal ganglia, thalamus, third ventricle, and posterior portion of pituitary gland (anterior from ectoderm)

Question 21

What is formed by saggital prosencephalon folding

Answer 21

Paired cerebral hemispheres, lateral ventricles, and portions of basal ganglia, only in telencephalon

Question 22

Thickening steps during Prosencephalic midline development

Answer 22

Commissural (Corpus callosum andSeptum pellucidum)

Chiasmatic (Optic chiasm)

Hypothalamic (Hypothalamus)

Question 23

What does the corpus collosum develop from

Answer 23

lamina terminalis

Question 24

What forms the choroid plexus

Answer 24

¨Tufts of capillaries invaginateinto roof plates of the forebrain & hindbrain

Question 25

Main events from week 9 to the end of gestation

Answer 25

¤Continued formation of sulci & gyri

¤Neuron Production, Migration, & Differentiation

¤Neuronal Apoptosis

Question 26

When do gyri and sulci form

Answer 26

Last 2 months of gestation

Question 27

When does neuron production peak

Answer 27

28 weeks

Question 28

Order of neuronal myelenation

Answer 28

1st: sensory pathways
2nd: motor pathways
3rd: association pathways