Embriology Flashcards

1
Q

Origin of epith of digestive tract + parenchyma of some glands

A

Endoderm

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2
Q

Origin of muscle walls of viscera + CT layers surrounding viscera

A

Mesoderm

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3
Q

Liver arises from

A

Liver bud

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4
Q

Liver bud protrudes into

A

Ventral mesogastrium

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5
Q

Ventral mesogastrium divides into

A

Gastrohepatic / lesser omentum
Falciform ligament

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6
Q

Gastrohepatic / lesser omentum connects

A

Stomach and liver

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7
Q

Falciform ligament connects

A

Liver to the ventral wall

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8
Q

Liver location

A

R side

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9
Q

Liver functions

A

Glycogen production
Albumin production
Protein metabolism
Bile secretion
Hematopoietic function (after embryonic splanchnic mesoderm)

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10
Q

Bile is stored in

A

Gallbladder

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11
Q

Gallbladder origin

A

Hepatic duct grows and gives it

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12
Q

Gallbladder is connected to the liver by

A

Cystic duct

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13
Q

Gallbladder reaches duodenum through

A

Common bile duct

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14
Q

Pancreas origin from

A

Ventral + dorsal pancreatic duct
They fuse and for the head, neck and body

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15
Q

Ventral pancreatic duct arises from

A

Common bile duct

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16
Q

Relation main pancreatic duct - duodenum

A

It opens through the common bile duct into the 2nd portion of the duodenum, so both hepatic and pancreatic secretions enter here to participate in digestion.

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17
Q

Accessory pancreatic duct origin

A

Dorsal pancreas duct that persist a persist as a little accessory pancreatic duct

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18
Q

Accessory pancreatic duct function

A

When the main pancreatic duct is blocked

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19
Q

Separation between the derivatives of the foregut and the derivatives from the midgut

A

Major duodenal papilla

20
Q

Major duodenal papilla marks

A

Point where main pancreatic duct and bile duct drain into duodenum

21
Q

Minor duodenal papilla

A

Where accessory pancreatic duct drains into the duodenum in case of blockage of the main one

22
Q

Stomach formation

A

It rotates around its long axis 90º clockwise —> behind it appears ommental bursa / lesser sac

Post walls grow faster —> increased curvature on L side

Cardiac portion: downwards
Pyloric portion: upwards

23
Q

Stomach is connected and attached by

A

Mesenteries

24
Q

Liver arises within

A

Ventral mesogastrium

25
Q

Pancreas and spleen arise within

A

Dorsal mesogastrium

26
Q

Dorsal mesogastrium gives rise to

A

Greater omentum

27
Q

Mesenteries definition

A

Double layer of peritoneum

28
Q

Mesenteries function

A

Connects viscera to dorsal and ventral walls

29
Q

Esophagus formation

A

From foregut ventral wall —> respiratory diverticulum that will be separated from esophagus by tracheoesophageal septum

30
Q

Anomalies in esophagus formation

A

Tracheoesophageal fistulas —> prenatal: polyhydramnios / postnatal: regurgitation)
Incomplete recanalization (stenosis)
Congenital hiatal hernia —> stomach herniates into thoracic cavity

31
Q

Midgut definition

A

Part of the gut tub that remains connected to the yolk sac after the folds progresses.
Connected to abdominal wall by dorsal mesentery through which arteries can access

32
Q

Midgut location

A

Inferiorly to major duodenal papilla -> junction prox 2/3 - distal 1/3 of transverse colon

33
Q

Disposition changes of the midgut

A

(Dorsal mesentery rotates along w/ structures)

5th week: U-shape loop has sup+inf limb & vitelline duct

6th week: midgut limb growth + not enough space = physiological herniation into umbilicus (90º rotation) —> sup limb to R (small intest loops), inf limb to L (large intest derivatives)

10th week: enough space -> physiolog hernia reduction —> inf limb also enters but rotates 180º

34
Q

Anomalies of the midgut development

A

Malrotation

Meckel’s diverticulum - by persistence of vitelline duct

Umbilical hernia - by unproperly abd musculature closure

Omphalocele - by failure of reduction of physiolog herniat.

Gastroschisis - by incomplete closure of lat folds (viscera bathed by amniotic fluid)

35
Q

Hindgut location

A

Begins just before L colic flexure/ splenic flexure
Ends in the cloacal membrane

36
Q

Caudal portion of the hindgut =

A

Cloaca

37
Q

Post to the cloaca is the

A

Allantois

38
Q

Allantois is related to

A

Bladder and urogenital system

39
Q

Hindgut is separated from allantois by

A

Urorectal septum

40
Q

Urorectal septum definition

A

Mesoderm ridge that will form the perineum

41
Q

Urorectal septum development

A

Will grow caudally and separate cloaca into
- ant: allantois
- post: rectum and anal canal

Will separate the cloacal membrane into
- urogenital membrane
- anal membrane

42
Q

Cloacal membrane gives rise to

A

Proctodeum

43
Q

Anal canal origins

A
  • 1º 2/3 of anal canal —> from hindgut
  • last 1/3 of anal canal -> from proctodeum (= ectoderm invagination)
44
Q

Last portion of anal canal innervation and irrigation

A

Innervation: somatic
Irrigation: inf and middle rectal veins -> common iliac veins

45
Q

Anal membrane rupture

A

8th week

46
Q

Congenital anomalies of the hindgut

A

Incorrect development of urorectal septum
- imperforate anus
- rectovaginal fistula
- fistula ureters-rectum
- rectal atresia

Megacolon/ Hirschsprung disease
(non-proper migration of NCC during 4-5th week = no PS ganglia = no peristalsis = food accumulation = dilation)