EM Navigational Bronchoscopy and EBUS Staging

Question 1

ENB creates a 3D map of the —- ?

Answer 1

Bronchial Tree

Question 2

EBUS is good for mediastinal area but not for — where most lung ca happens (ACA)

Answer 2

periphery

Question 3

What is the benefit of EBUS?

Answer 3

Eliminate collapsed lung out of the picture (pneumothorax) & monitoring patient after the procedure

Question 4

—– & —– fiducial markers are implanted during an ENB™ procedure (also known as an Electromagnetic Navigation Bronchoscopy™ procedure) to mark the location of diseased lung tissue for future treatments.

Answer 4

superLock and superDimension

Question 5

Function of Fiducial markers?

Answer 5

Maintain electrical field; allows radiation to perform on spot w/o radiation spreading outside of these markers

Question 6

To stage lung cancer: lymph nodes are sample – at least —- should be sampled

Answer 6

Three (3)

Question 7

what is the appropriate response to seeing granuloma on EBUS?

Answer 7

Send for culture

Question 8

Reactive lymph nodes + Hx of lymphoma

Answer 8

Send for Flow Cytometry

Question 9

—- and point mutations are the most commonly found mutations that are associated with response to TKIs.

Answer 9

EGFR exon 19 deletions, L858R

Question 10

What does EGFR stands for?

Answer 10

Epidermal Growth Factor Receptor

Question 11

TKI is —-?

Answer 11

Tyrosine Kinase Inhibitor

Question 12

This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4.

Answer 12

EGFR

Question 13

This gene has been found to be rearranged, mutated, or amplified in a series of tumors including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer.

Answer 13

ALK