EM Navigational Bronchoscopy and EBUS Staging Flashcards
ENB creates a 3D map of the —- ?
Bronchial Tree
EBUS is good for mediastinal area but not for — where most lung ca happens (ACA)
periphery
What is the benefit of EBUS?
Eliminate collapsed lung out of the picture (pneumothorax) & monitoring patient after the procedure
—– & —– fiducial markers are implanted during an ENB™ procedure (also known as an Electromagnetic Navigation Bronchoscopy™ procedure) to mark the location of diseased lung tissue for future treatments.
superLock and superDimension
Function of Fiducial markers?
Maintain electrical field; allows radiation to perform on spot w/o radiation spreading outside of these markers
To stage lung cancer: lymph nodes are sample – at least —- should be sampled
Three (3)
what is the appropriate response to seeing granuloma on EBUS?
Send for culture
Reactive lymph nodes + Hx of lymphoma
Send for Flow Cytometry
—- and point mutations are the most commonly found mutations that are associated with response to TKIs.
EGFR exon 19 deletions, L858R
What does EGFR stands for?
Epidermal Growth Factor Receptor
TKI is —-?
Tyrosine Kinase Inhibitor
This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4.
EGFR
This gene has been found to be rearranged, mutated, or amplified in a series of tumors including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer.
ALK